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颅内血管外皮细胞瘤(hemangiopericytoma,HPC)是起源于脑膜间质的恶性肿瘤,发生率较低,约占所有原发性中枢神经系统肿瘤的0.4%[1],术后可发生颅外转移,常见部位是骨、肺及肝,目前国内报道较少。
颅内间变性血管外皮细胞瘤伴骨转移一例
Intracranial anaplastic hemangiopericytoma with bone metastasis: a case report
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摘要: 笔者报道了1例颅内间变性血管外皮细胞瘤(AHPC)伴骨转移的病例,从临床表现、影像学检查尤其是全身骨显像检查以及术后病理综合分析了该病特点。并通过文献复习加深了对AHPC骨转移的认识。多数恶性肿瘤常见骨转移,而颅内AHPC是一种少见的中枢神经系统肿瘤,较少发生骨转移。通过全身骨显像发现了该例患者多处骨骼病变,术后病理提示颅内AHPC骨转移,因此提示恶性肿瘤尤其是少见骨转移者应把骨显像检查作为随访的一个重要检查,对于早期发现骨转移、确定临床分期及治疗方案的选择等都是至关重要的。Abstract: A case of bone metastase secondary to intracranial anaplastic hemangiopericytoma (AHPC) was reported. The characteristics of the disease were analyzed on the basis of clinical symptoms and imaging examinations, especially bone imaging examination and pathology. The understanding of intracranial AHPC bone metastasis was deepened by literature review. Bone metastases are common in most malignant tumors, but intracranial AHPC, which is a rare central nervous system tumor, has an extremely low bone metastasis potential. In the present case, the multiple lesions of bone metastasis from intracranial AHPC were detected through a whole body bone imaging examination. Thus, whole body bone scans should be regarded as important examination tools for patients with malignant tumors during follow-up, especially patients with rare bone metastasis, because the scans have a key value in early detection, clinical staging, and treatment decision.
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