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世界卫生组织将甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)规定为肿瘤直径≤10 mm的甲状腺癌[1]。近年来,由于高分辨率超声、超声造影及超声引导下细针穿刺活检等检查手段的发展,PTMC的检出率逐年上升。PTMC大多局限在甲状腺内,仅少数有腺外侵犯、颈淋巴结转移和远处转移等侵袭特点,因此,对于直径>1 cm的甲状腺乳头状癌的治疗方案并不完全适用于PTMC,临床医师对PTMC的治疗争议较大[2]。现将PTMC治疗中争议较大的问题综述如下。
甲状腺微小乳头状癌的治疗进展
Progress in the treatment of papillary thyroid microcarcinoma
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摘要: 甲状腺癌,特别是甲状腺微小乳头状癌(PTMC)总体预后良好,因此以往临床医师没有足够重视。近年来,随着PTMC的发病率越来越高,学者对其研究更加深入,国际指南和国内专家均对其越来越重视,对其诊治做了相应推荐。由于缺乏大量的循证医学证据,目前国内外对PTMC的诊治还存在许多争议,笔者对PTMC治疗中争议较大的问题进行综述。Abstract: In the past, clinicians paid little attention to thyroid cancers, particularly papillary thyroid microcarcinoma (PTMC), given their good overall prognoses. Recently, however, international and domestic researchers have given increased attention to PTMC and its diagnosis and treatment because of the increasing incidence of this malignancy. The diagnosis and treatment of PTMC remain controversial at home and abroad given their lack of evidence-based medical evidence. This paper summarizes the controversies surrounding the treatment of PTMC.
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Key words:
- Thyroid neoplasms /
- Therapy /
- Follow-up /
- Hormone suppression
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