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99Tcm-MDP全身骨显像是核医学最常用的检查项目之一,主要用于探测恶性病变骨转移及良性骨骼病变。临床工作中,在排除技术原因及体表污染等常见因素后,时常会发现骨外软组织异常显影的现象,其中以腹盆部居多。目前,骨外组织病理性摄取的原因及机制尚不明确[1-2]。一项对1060例患者骨扫描图像进行分析的结果显示,骨外软组织异常显影的发生率为5.4%[1]。笔者通过查阅国内外相关文献,对骨外摄取的可能机制,尤其是腹盆部软组织异常显影的原因进行总结,以期为临床工作提供帮助。
99Tcm-MDP全身骨显像腹盆部软组织异常显影的原因分析
Analysis of abdominal and pelvic extraosseous uptake of 99Tcm-methylene diphosphonate on bone scintigraphy
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摘要: 99Tcm-亚甲基二膦酸盐(99Tcm-MDP)骨扫描具有无创、全身显像的优势,在诊断骨骼疾病尤其是筛查骨转移癌方面具有重要价值。但骨扫描图像上有时会出现骨外异常摄取,以腹盆部居多。目前,骨外摄取的机制尚不明确,系统全面了解引起骨外摄取的原因有助于图像的准确判读,减少盲目检查,从而提高骨扫描的诊断价值。笔者就当前相关文献中腹盆部软组织异常显影的可能原因进行综述,以期为临床诊疗提供一定帮助。Abstract: The advantage of noninvasive and whole body imaging makes bone scintigraphy play an important role in the diagnosis of bone diseases, especially in exploring bone metastasis. However, extraosseous uptake on bone scintigraphy has been observed in some instances. Presently, the mechanism of extraosseous uptake is still unclear. Identification of such nonosseous uptake can reduce the blind examinations and improve the diagnostic value of bone scintigraphy. The author reviews the related articles that illustrate the possible causes of extraosseous uptake in the abdominal and pelvic soft tissues to provide essential help for clinical diagnosis.
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Key words:
- Technetium Tc 99m methylene /
- Bone scintigraphy /
- Extraosseous uptake /
- Abdominal pelvis
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