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卵巢癌是病死率最高的妇科恶性肿瘤。与CA125、超声、CT、MRI等常规检查相比,18F-FDG PET/CT对卵巢癌的诊断、分期、疗效及预后的评估具有明显的优势,它既可以显示解剖结构以精确定位肿瘤,又可以显示肿瘤细胞葡萄糖的代谢活性,指导临床采取有针对性的治疗方案。与18F-FDG PET/CT相比,18F-FDG PET/MRI有着更高的软组织分辨率,并且其为多序列成像,减少了辐射剂量。笔者对18F-FDG PET/CT及18F-FDG PET/MRI在卵巢癌中的临床应用进行综述。
18F-FDG PET/CT与18F-FDG PET/MRI在卵巢癌临床应用中的进展
Advances in clinical application of 18F-FDG PET/CT and 18F-FDG PET/MRI in ovarian cancer
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摘要: 卵巢癌是妇科恶性肿瘤中病死率最高的肿瘤。18F-FDG PET/CT在卵巢癌的诊断、分期、疗效及预后的评估上优于常规影像技术,可以指导临床采取有针对性的治疗方案,以获得更好的治疗效果。PET/MRI是最近几年继PET/CT后投入临床应用的另外一种多模态影像技术,因其多序列成像、软组织分辨率较高和辐射剂量较低,对卵巢癌的诊治具有独特的优势。笔者对18F-FDG PET/CT和18F-FDG PET/MRI在卵巢癌中的临床应用进行综述。
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关键词:
- 正电子发射断层显像计算机体层摄影术 /
- 正电子发射断层显像术 /
- 磁共振成像 /
- 卵巢肿瘤 /
- 肿瘤转移 /
- 复发
Abstract: Among all gynecological malignancies, ovarian cancer has the highest mortality rate. In the diagnosis and staging of ovarian cancer, 18F-FDG PET/CT is superior to conventional imaging. It is used to assess the prognosis of patients with ovarian cancer and the curative effects of ovarian cancer treatments. In addition, it can be used to guide clinical treatment to improve therapeutic effect. 18F-FDG PET/MRI is a multimodal imaging technique that has been recently applied in clinical practice. It exhibits unique advantages in the diagnosis of ovarian cancer given its characteristics of multiple-sequence imaging, high soft-tissue resolution, and low radiation dosage. This review presents an overview of the application of 18F-FDG PET/CT and 18F-FDG PET/MRI in the diagnosis and staging of ovarian cancer. -
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