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肿瘤是危害人类健康的最重要问题之一。目前, 世界上大约有1/3的人患癌肿, 并且有1/4的人死于癌肿[1]。准确地评估肿瘤患者的淋巴结及难以解释的淋巴结病变, 对选择合适的治疗计划及预后的判断至关重要。淋巴结切除术后活检曾被认为是淋巴结评估的金指标。然而, 外科手术的费用高且具有侵袭性, 会带来很多复杂的并发症; 并且, 手术视野外的淋巴结容易遗漏, 这些就限制了手术的治疗。目前, 研究的重点主要在于对淋巴结病变的早期诊断。近年来, 影像学技术对淋巴结的诊断发挥着非常重要的作用, 它采用非侵袭性技术对全身淋巴结进行评估, 包括CT、MRI、PET、淋巴结造影术等, 不同的影像学方法在评价局部淋巴结时具有各自的特点。本文就超声检查、CT、MRI、PET方面做一综述。
影像学技术对转移性淋巴结的诊断价值
Diagnosis value of imaging techniques in assessing lymph nodes metastasis
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摘要: 早期准确地评估肿瘤患者的淋巴结及难以解释的淋巴结病变,对选择合适的治疗计划及预后的判断至关重要。目前,淋巴结大小仍然是区别转移性和非转移性淋巴结的最常用的指标,但是其准确性不高,为了提高对淋巴结良恶性病变评估的准确性,需要找到一种新的显像方法,它并不仅仅局限于对淋巴结解剖上的评估,还可以在细胞水平对淋巴结生理和生化过程进行直观和定量评估。不同的影像学方法在评价局部淋巴结时具有各自的特点,随着分子影像学的发展,功能成像技术在淋巴结诊断方面占据着越来越重要的地位。该文旨在对诊断淋巴结转移的各种影像学技术做一综述。
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关键词:
- 淋巴结 /
- 肿瘤转移 /
- 超声检查 /
- 磁共振成像 /
- 体层摄影术, X线计算机 /
- 正电子发射断层显像术
Abstract: Early and accurate evaluate the patients'lymph nodes and the unexplained lymphadenopathy are crucial to select the proper treatment plan and dpredicting prognosis.Although size measurements are still the most widely used method for discriminating malignant from non-malignant lymph nodes, it possesses a low accuracy.In order to increase the accuracy of evaluate the malignant and benign lymph nodes, it is necessary to find a new imaging method which is not just evaluate the anatomical structures of the lymph node, but also allow visualization and quantification of physiological and biochemical processes at the cellular level.Every imaging technique has its own characteristic to evaluate local lymph nodes, with the persistent development of molecular imaging, functional imaging technique has played a more and more important role in the diagnosis of lymph nodes.This article mainly reviewed and discussed imaging techniques in the evaluation of lymph nodes. -
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