18F-FLT对恶性肿瘤治疗效果的评估价值

李红梅 冯珏 李晓东 张建阳

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18F-FLT对恶性肿瘤治疗效果的评估价值

    通讯作者: 冯珏, feng-jue@163.com

The value of 18F-fluorothymidine to monitor the therapeutic effect of malignant tumor

    Corresponding author: FENG Jue, feng-jue@163.com ;
  • 摘要: 形态影像学作为评价恶性肿瘤治疗效果的传统方法,因所需时间较长,不能从生物学角度进行评价,逐渐被分子影像学方法所取代。18F-氟脱氧葡萄糖(18F-FDG)PET虽然在多种肿瘤的诊断、分期及疗效监测中显示了突出的优势,但由于特异性较差,不能对恶性肿瘤的治疗效果进行准确评价。研究表明,18F-氟胸苷(18F-FLT)PET最大的应用前景在于监测肿瘤的治疗效果,且优于18F-FDG。
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  • 收稿日期:  2009-01-05

18F-FLT对恶性肿瘤治疗效果的评估价值

    通讯作者: 冯珏, feng-jue@163.com
  • 河北医科大学第二医院核医学科, 石家庄 050000

摘要: 形态影像学作为评价恶性肿瘤治疗效果的传统方法,因所需时间较长,不能从生物学角度进行评价,逐渐被分子影像学方法所取代。18F-氟脱氧葡萄糖(18F-FDG)PET虽然在多种肿瘤的诊断、分期及疗效监测中显示了突出的优势,但由于特异性较差,不能对恶性肿瘤的治疗效果进行准确评价。研究表明,18F-氟胸苷(18F-FLT)PET最大的应用前景在于监测肿瘤的治疗效果,且优于18F-FDG。

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