99Tcm-聚合白蛋白肺灌注显像对肺栓塞溶栓疗效的评价

董华 ,  张遵城 ,  郭永涛 ,  肖连东

downloadPDF
文章导航 > 国际放射医学核医学杂志  > 2009,  33 > 2: (76-79)  
引用本文:
shu
Citation:
shu

99Tcm-聚合白蛋白肺灌注显像对肺栓塞溶栓疗效的评价

  • 天津医科大学第二医院核医学科, 天津 300211

Evaluation of 99Tcm-macroaggregated albumin pulmonary perfusion imaging to thrombolytic therapy in pulmonary embolism

  • Department of Nuclear Medicine, The Second Hospital of Tianjin Medical University, Tianjin 300211, China

  • 摘要: 目的 探讨99Tcm-聚合白蛋白(99Tcm-MAA)肺灌注显像评价肺栓塞溶栓治疗的价值.方法 对54例急性肺栓塞的患者进行回顾性分析,所有患者均由99Tcm-MAA肺灌注显像结合X线胸片检查确诊,并于溶栓治疗1周后复查肺灌注显像,部分病例于治疗3个月后再次复查.结果 54例急性肺栓塞患者溶拴治疗前99Tcm-MAA肺灌注显像共观察到347个受损肺段,X线胸片均无相应肺段或亚肺段异常.溶栓治疗后1周复查肺灌注显像,164个受损肺段(47.3%)恢复正常;3个月后再次复查,199个受损肺段(57.4%)恢复正常(χ2=10.68,P<0.05).结论 99Tcm-MAA肺灌注显像是一种无创的诊断方法,对肺栓塞溶栓治疗效果的评估有重要价值.
    Abstract: Objective To investigate the role of 99Tcm-macroaggregated albumin (99Tcm-MAA)pulmonary perfusion imaging in evaluating thrombolytic therapy in pulmonary embolism. Methods Date of 54 patients with acut pulmonary embolism diagnosed by 99Tcm-MAA pulmonary perfusion imaging combined with radiography were analyzed retrospectively. Among them, pulmonary perfusion imaging was also performed one week after thrombolytic therapy. In some cases, pulmonary perfusion imaging was performed three months after thrombolytic therapy. Results The results of radiography were normal in all cases, among 347 abnormal pulmonary segments in 54 cases. 164 (47.3%) and 199 (57.4%) segments were restored to normal 1 week and 3 months later(χ2=10.68, P<0.05). Conclusion As a non-invasive diagnostic method,99Tcm-MAA pulmonary perfusion imaging play an important role in evaluating the therapeutic effectiveness of thrombolytic therapy in patients with pulmonary embolism.
  • [1] 陈爱萍,于红,肖湘生.肺栓塞的影像学研究进展及临床诊断策略.国外医学临床放射学分册,2007,30(5):309-312.
    [2] Kyrle PA, Eiehinger S. Deep vein thrombosis. Lancet, 2005, 365(9465):1163-1174.
    [3] Olin JW. Pulmonary embolism. Rev Cardiovasc Med, 2002, 3(Suppl 2):S68-S75.
    [4] Tilli P, Testa A, Covino M, et al. Diagnostic and therapeutic approach to acute pulmonary embolism in an emergency department. Eur Rev Med Pharmacol Sci, 2006, 10(2):91-98.
    [5] 臧任丽,孙国超,杨有万,等.急性肺动脉栓塞的螺旋CT诊断.中国CT和MRI杂志,2006,4(1):38-39.
    [6] 王辰.肺栓塞.北京:人民卫生出版社,2003.65-71.
    [7] Oudkerk M, van Beek EJ, Wielopolski P, et al. Comparison of contrast-enhanced magnetic resonance angiography and conventional pulmonary angiography for the diagnosis of pulmonary embolism:a prospective study. Lancet, 2002, 359(9318):1643-1647.
    [8] Stein PD, Henry JW, Gottschalk A. Reassessment of pulmonary angiography for the diagnosis of pulmonary embolism:relation of interpreter agreement to the order of the involved pulmonary arterial branch. Radiology, 1999, 210(3):689-691.
    [9] Stein PD, Athanasoulis C, Alavi A, et al. Complications and validity of pulmonary angiography in acute pulmonary embolism. Circulation, 1992, 85(2):462-468.
    [10] 周前.中华影像医学一影像核医学卷.北京:人民卫生出版社,2002:93-94.
    [11] Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med, 2006,354(22):2317-2327.
    [12] Ost D, Rozenshtein A, Saffran L, et al. The negative predictive value of spiral computed tomography for the diagnosis of pulmonary embolism in patients with nondiagnostic ventilationperfusion scans, Am J Med, 2001, 110(1):16-21.
    [13] Hamel E, Pacouret G, Vincentelli D, et al. Thrombolysis or heparin therapy in massive pulmonary embolism with right ventricular dilation:results from a 128-patients monocenter registry. Chest, 2001, 120(1):120-125.
  • [1] 郭宵峰 , 刘建中 , 孙琦婷 . 肺通气/灌注平面显像与肺灌注SPECT/CT对肺栓塞诊断价值的对比性研究. 国际放射医学核医学杂志, 2015, 39(4): 277-281. doi: 10.3760/cma.j.issn.1673-4114.2015.04.001
    [2] 安彩霞 , 刘建中 , 杨丽娟 . 64层螺旋CT肺血管造影在肺栓塞诊疗中的应用价值. 国际放射医学核医学杂志, 2010, 34(6): 367-369. doi: 10.3760/cma.j.issn.1673-4114,2010.06.013
    [3] 安彩霞 , 刘建中 , 杨丽娟 . 64层螺旋CT肺血管造影在肺栓塞诊疗中的应用价值. 国际放射医学核医学杂志, 2010, 34(6): 367-369. doi: 10.3760/cma.j.issn.1673-4114.2010.06.013
    [4] 彭武和 , 程静 , 曹庆东 . 核素肺通气/灌注显像在肺栓塞诊断中的现状及进展. 国际放射医学核医学杂志, 2012, 36(2): 80-83. doi: 10.3760/cma.j.issn.1673-4114.2012.02.005
    [5] 陆克义 , 刘德峰 , 刘建中 , 胡光 , 李险峰 , 李思进 . 肺灌注显像Meyer评分在肺栓塞疗效评价中的应用. 国际放射医学核医学杂志, 2009, 33(5): 265-267. doi: 10.3760/cnla.j.issn.1673-4114.2009.05.003
    [6] 杨心蕊 , 卫华 , 郝新忠 , 武萍 , 武志芳 . 过敏性肺炎伴左肺动脉栓塞18F-FDG PET/CT误诊肺癌一例. 国际放射医学核医学杂志, 2014, 38(2): 135-136, 139. doi: 10.3760/cma.j.issn.1673-4114.2014.02.014
    [7] 周云 , 刘璐 , 宋进华 . 经肝动脉灌注90Y微球治疗肝癌的研究进展. 国际放射医学核医学杂志, 2006, 30(6): 321-324.
    [8] 黄平治 , 杭南燕 , 谭天秩 . 肺放射性核素断层扫描诊断肺栓塞. 国际放射医学核医学杂志, 1982, 6(3): 193-194.
    [9] 单越芬 , 赵惠杨 , 张金谷 . 99m锝体内标记红细胞诊断深静脉栓塞. 国际放射医学核医学杂志, 1981, 5(4): 253-253.
    [10] 兰继承 . 怀疑肺栓塞肺灌注扫描期间偶然发现甲亢. 国际放射医学核医学杂志, 1992, 16(1): 44-45.
  • 加载中
WeChat 点击查看大图
计量
  • 文章访问数:  1729
  • HTML全文浏览量:  289
  • PDF下载量:  2
出版历程
  • 收稿日期:  2008-10-08

99Tcm-聚合白蛋白肺灌注显像对肺栓塞溶栓疗效的评价

  • 天津医科大学第二医院核医学科, 天津 300211
  • 收稿日期: 2008-10-08

摘要: 目的 探讨99Tcm-聚合白蛋白(99Tcm-MAA)肺灌注显像评价肺栓塞溶栓治疗的价值.方法 对54例急性肺栓塞的患者进行回顾性分析,所有患者均由99Tcm-MAA肺灌注显像结合X线胸片检查确诊,并于溶栓治疗1周后复查肺灌注显像,部分病例于治疗3个月后再次复查.结果 54例急性肺栓塞患者溶拴治疗前99Tcm-MAA肺灌注显像共观察到347个受损肺段,X线胸片均无相应肺段或亚肺段异常.溶栓治疗后1周复查肺灌注显像,164个受损肺段(47.3%)恢复正常;3个月后再次复查,199个受损肺段(57.4%)恢复正常(χ2=10.68,P<0.05).结论 99Tcm-MAA肺灌注显像是一种无创的诊断方法,对肺栓塞溶栓治疗效果的评估有重要价值.

English Abstract

    全文HTML

参考文献 (13)

目录

    /

    返回文章
    返回

    版权所有©中华医学会   备案号：津ICP备15006720号-3

    地址：天津市南开区白堤路238号电话：86-22-58089989
    86-22-85682389    传真：022-87890607

    本系统由 北京仁和汇智信息技术有限公司 开发 技术支持： info@rhhz.net