核医学影像技术在心肌炎诊断中的应用

邓惠兴; 马爱群

doi:10.3760/cma.j.issn.1673-4114.2009.01.039

核医学影像技术在心肌炎诊断中的应用

邓惠兴 , 马爱群

文章导航 > 国际放射医学核医学杂志 > 2009, 33 > 1: (39-42)

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核医学影像技术在心肌炎诊断中的应用

邓惠兴¹,
马爱群²

1. 西安交通大学第一附属医院核医学科, 西安 710061;
2. 西安交通大学第一附属医院心内科, 西安 710061

The application of radionuclide imaging technology in myocarditis

DENG Hui-xing¹,
MA Ai-qun²

1. Department of Nuclear Medicine, the 1st Affiliated Hospital of Xi'an Jiao Tong University, Xi'an 710061, China;
2. Department of Cardiology, the 1st Affiliated Hospital of Xi'an Jiao Tong University, Xi'an 710061, China

摘要: 核医学影像技术是一类无创性诊断心肌炎的方法。该文对各种核医学影像技术在心肌炎的实验研究结果和临床应用进行分析和评价,从心肌组织炎症、细胞坏死、细胞凋亡三个不同显像角度,比较了不同放射性核素、核素标记化合物的优势和不足。
- 心肌炎 /
- 放射性核素显像 /
- 细胞凋亡
Abstract: Radionuclide imaging is a sort of non-invasive diagnostic technology in myocarditis. This paper is to make a view of these methods diagnosing myocarditis on clinical application and the results of experiment in vivo. From three different aspects:cell death, cell apoptosis and myocardium inflammatory, different radlonuclines and labelled compounds were compared.
- Myocarditis /
- Radionuclide imaging /
- Apoptosis
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

[1]	O'Connell JB,Henkin RE,Robinson JA,et al.Gallium-67 imaging in patients with dilated eardiomyopathy and biopsy-proven myocarditis.Circulation,1984,70(1):58-62.
[2]	Matsuura H,Ishikita T,Yamamoto S,et al.Gallium-67 myocardial imaging for the detection of myocarditis in the acute phase of Kawasaki disease (mueocutaneous lymph node syndrome):the usefulness of single photon emission computed tomography.Br Heart J,1987,58(4):385-392.
[3]	van Eerd JE,Broekema M,Harris TD.Imaging of infection and inflammation with an improved ^99mTc-labeled LTB4 antagonist.J Nucl Med,2005,46(9):1546-1551.
[4]	Broekema M,van Eerd JJ,Oyen WJ,et al.Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci.J Med Chem,2005,48(20):6442-6453.
[5]	Aparici CM,Narula J,Puig M,et al.Somatostatin receptor scintigraphy predicts impending cardiac allograft rejection before endomyocardial biopsy.Eur J Nucl Med,2000,27(12):1754-1759.
[6]	Dec GW,Palacios I,Yasuda T,et al.Antimyosin antibody cardiac imaging:its role in the diagnosis of myocarditis.J Am Coll Cardiol,1990,16(1):97-104.
[7]	Martin ME,Moya-Mur JL,Casanova M,et al.Role of noninvasive antimyosin imaging in infants and children with clinically suspected myocarditis.J Nucl Med,2004,45(3):429-437.
[8]	Flotats A,Carrio I.Non-invasive in vivo imaging of myocardial apoptosis and necrosis.Eur J Nucl Med Mol Imaging,2003,30(4):615-630.
[9]	Sun Y,Ma P,Bax JJ,et al.^99mTc-MIBI myocardial perfusion imaging in myoearditis.Nucl Med Commun,2003,24(7):779-783.
[10]	Peker C,Sarda-Mantel L,Loisean P,et al.Imaging apoptosis with ^99mTc-annexin-V in experimental subaeute myocarditis.J Nacl Med,2004,45(6):1081-1086.
[11]	Tokita N,Hasegawa S,Maruyama K,et al.^99mTc-Hynic-annexin V imaging to evaluate inflammation and apoptesis in rats with autoimmune myocantitis.Eur J Nucl Med Mol Imaging,2003,30(2):232-238.

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