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McCune-Albright综合征(McCune-Albright syndrome,MAS)是一种罕见且复杂的疾病。影像检查可通过骨纤维结构不良(fibrous dysplasia of bone,FDB)的检出辅助MAS的临床诊断。全身骨显像是诊断FDB的一种重要的影像方法,一次显像可灵敏、直观地评价全身骨骼病变的部位、范围、程度。本文报道了1例行 99Tcm-MDP全身骨显像的MAS病例,最终经组织病理学检查结果确诊,并通过文献复习其临床和影像特征,以期提高对该病的认识和诊断。
McCune-Albright综合征99Tcm-MDP全身骨显像1例
99Tcm-MDP whole body bone imaging of McCune-Albright syndrome: a case report
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摘要: 笔者报道了1例McCune-Albright综合征(MAS)99Tcm-亚甲基二膦酸盐(MDP)全身骨显像的病例,显像结果表现为全身多处显像剂摄取异常增高灶,并通过X线、CT和MRI影像全面评估,经组织病理学检查结果证实为多发性骨纤维结构不良(FDB)。MAS临床上少见,笔者分别从临床特点及影像表现等方面分析了该病的特点,并结合文献复习了不同部位FDB的99Tcm-MDP全身骨显像特征,以为其诊断提供更多参考。Abstract: The authors reported a case of 99Tcm-methylenediphosphonate(MDP) whole-body bone imaging in a child with McCune-Albright syndrome (MAS). The imaging showed multiple abnormal hyperactive and elevated bone metabolism, and were comprehensively evaluated by X-ray, CT and MRI imaging. Pathological examination confirmed the diagnosis of multiple fibrous dysplasia of bone (FDB). MAS is rare in clinical, the authors analyzed the characteristics of MAS from the clinical characteristics and imaging manifestations respectively, and combined with the literature review of 99Tcm-MDP whole body bone imaging features of FDB in different parts, which to provide more references for its diagnosis.
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