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在甲状腺恶性肿瘤中,DTC约占95%[1],其恶性程度较低,预后相对较好。隐匿性甲状腺癌(occult thyroid carcinoma,OTC)是DTC的一个特殊亚型,因发病隐匿常被漏诊。尽管有研究结果显示,OTC占所有甲状腺癌的6%以上[2],但发生全身广泛转移的OTC病例在国内外鲜有报道。笔者分析了1例经组织病理学检查证实的OTC病例,探讨OTC发生的可能原因及其全身广泛转移的治疗方案。
全身广泛转移的隐匿性甲状腺滤泡状癌1例
Occult follicular thyroid carcinoma with extensive systemic metastasis: a case report
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摘要: 隐匿性甲状腺癌(OTC)在分化型甲状腺癌(DTC)中较为少见,而全身广泛转移的OTC病例国内外更是极少报道。笔者报道了1例全身骨骼、双肺、肾上腺等部位广泛转移但未发现原发灶的甲状腺滤泡状癌病例,通过分析其诊疗经过、实验室检查、组织病理学检查结果并复习相关文献,探讨OTC发生的可能原因及其全身广泛转移的治疗方案。Abstract: Occult thyroid carcinoma (OTC) is rare in differentiated thyroid carcinoma (DTC), and cases of OTC with extensive systemic metastasis are rarely reported at home and abroad. This paper reported a case of follicular carcinoma of thyroid with extensive metastasis from skeleton, lungs, adrenal gland and other parts of the whole body without primary focus, by analyzing the diagnosis and treatment process, laboratory examination, histopathological examination results and reviewing the relevant literature, the possible causes of OTC and the treatment scheme of extensive metastasis in the whole body were discussed.
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