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多发性周围神经病、脏器肿大、内分泌病变、M蛋白和皮肤病变(polyneuropathy,organomegaly,endocrinopathy,monoclonal protein,skin changes,POEMS)综合征是一种与浆细胞病有关的多系统病变,临床上较罕见,其以多发性周围神经病变、器官肿大、内分泌障碍、M蛋白血症和皮肤病变为特征[1],该临床表现由Crow[2]在1956年首次进行描述。1980年,Bardwick等[3]首次将该病主要症状的首字母组合,命名为POEMS综合征。POEMS综合征的发病率约为3/1 000 000,男性的发病率稍高于女性,高发年龄段为50~70岁。我们报道了1例中年男性POEMS综合征患者,对其临床及影像资料进行分析,并对文献报道进行回顾,以提高临床医师对该病的认识。
POEMS综合征18F-FDG PET/CT显像一例及文献复习
18F-FDG PET/CT imaging of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes (POEMS) syndrome: a case report and review of the literature
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摘要: 笔者报道了1例多发性周围神经病、脏器肿大、内分泌病变、M蛋白和皮肤病变(POEMS)综合征累及右侧髂骨的18F-氟脱氧葡萄糖(FDG)PET/CT显像的病例,并通过文献复习回顾总结了POEMS综合征的诊断标准及18F-FDG PET/CT的影像表现。POEMS综合征18F-FDG PET/CT显像的报道较多,但影像表现只累及右侧髂骨的病例较少见。了解POEMS综合征的诊断标准、临床表现及实验室检查结果,有助于获取更多的信息并进行准确诊断。Abstract: The authors reported a case of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes (POEMS) syndrome located in the right iliac bone by 18F-fluorodeoxyglucose (FDG) PET/CT. The authors summarized the diagnostic criteria and 18F-FDG PET/CT imaging manifestations of POEMS syndrome through literature review. Although 18F-FDG PET/CT in POEMS syndrome has been well reported, imaging manifestations involving only the right iliac bone are rare. Understanding the diagnostic criteria, clinical manifestations and laboratory findings of POEMS syndrome can help to obtain more information and make an accurate diagnosis.
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