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非骨化性纤维瘤(non-ossifying fibroma,NOF) 是由成熟的非成骨性结缔组织发育而来的良性骨肿瘤,临床上较为少见,约占原发性骨肿瘤的1.1%。 Jaffe等[1]在1941年首次认识了它,并在第2年由Jaffe 和 Lichtenstein正式命名。NOF多见于10~20岁的青少年男性,病变部位多见于股骨下端和胫骨上端,常为单灶发病。本文报道的是1例发生在中年女性患者身上的经术后病理结果证实的NOF,对其影像资料进行回顾性分析,并结合文献复习,旨在提高临床医师对该病的认识。
非骨化性纤维瘤18F-FDG PET/CT显像1例及文献回顾
18F-FDG PET/CT imaging of non-ossifying fibroma: one case report and literature review
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摘要: 笔者报道了1例发生在中年女性右侧胫骨近端的非骨化性纤维瘤(NOF)的X线、磁共振成像及PET/CT影像表现,并通过文献回顾总结了NOF的18F-氟脱氧葡萄糖(FDG) PET/CT影像表现。关于NOF的18F-FDG PET/CT检查的报道不多,充分认识其影像征象,有助于获取更多的信息,进而做出准确诊断。Abstract: The authors reported a case of non-ossifying fibroma (NOF) located in the cortical layer of the proximal tibia of a middle-aged woman. The characteristics of NOF were analyzed from X-ray, magnetic resonance imaging and 18F-fluorodeoxyglucose (FDG) PET/CT. The imaging features on 18F-FDG PET/CT were summarized through literature review. NOF can show mild-to-moderate 18F-FDG uptake on PET/CT. There are few reports on 18F-FDG PET/CT examination of NOF. So emphasize the awareness of this situation and get full understanding of its imaging signs are particularly important to get more information and make accurate diagnosis.
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