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上皮样血管内皮瘤(epithelioid angiosarcoma,EA)是一种来源于血管内皮细胞的恶性肿瘤,该病具有高度侵袭性和破坏性[1],在深部软组织较常见[2],原发于骨组织较为罕见[3] 。99Tcm-MDP全身骨显像可观察全身骨质情况,并且SPECT/CT融合显像作为全身骨显像的有效补充,将组织代谢情况与形态学表现相结合能更好地了解病灶的改变[4]。本文报道了1例发生于股骨的EA病例,查阅文献并分析其99Tcm-MDP SPECT/CT 显像特点,旨在为临床鉴别诊断提供参考。
股骨上皮样血管肉瘤99Tcm-MDP SPECT/CT显像一例
99Tcm-MDP SPECT/CT imaging in epithelioid angiosarcoma of the femur: a case report
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摘要: 骨上皮样血管肉瘤(EA)是来源于血管内皮细胞的高度恶性骨肿瘤,临床上较为罕见。笔者报道了1例经组织病理学检查证实的发生于股骨的EA病例,分别从临床表现、实验室检查、CT及99Tcm-亚甲基二膦酸盐(MDP) SPECT/CT全身骨显像等方面分析了该病的特点,并通过文献复习总结了EA的影像学特征。99Tcm-MDP SPECT/CT显像能发现转移灶并与其他疾病进行鉴别诊断,具有一定的临床价值。Abstract: Bone epithelioid angiosarcoma (EA) is a highly malignant bone tumor of vascular endothelial origin. Bone EA is a rare disease in clinical practice. A case of femoral EA with 99Tcm-methylenediphosphonate (MDP) SPECT/CT was reported and reviewed in terms of clinical symptoms, laboratory examination, CT and 99Tcm-MDP SPECT/CT imaging, the imaging features of EA were summarized by literature review. 99Tcm-MDP SPECT/CT imaging is helpful for the detection of metastatic and the differential diagnosis of EA from other diseases, which has certain clinical significance.
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