Abstract: Dendrimer materials emerging in recent years have become excellent materials for constructing nano-drug delivery systems due to their controllable structures and unique interactions with cell membranes and various active drug molecules, and have been widely studied in the field of tumor targeted therapy. As nanomolecules with good biocompatibility, dendrimers can be conjugated to tumor-targeting molecules to specifically deliver active drug molecules to tumor tissues, which can maximize drug targeting and reduce toxic effects on non-target tissues. In this paper, the recently research progress of nano-drug delivery systems based on dendrimer materials for tumor targeted therapy is reviewed.