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心肌灌注显像(myocardial perfusion imaging,MPI)是一种无创性检查技术,广泛应用于冠状动脉粥样硬化性心脏病(简称冠心病)的诊断及预后预测等[1]。但用于MPI的传统SPECT面临着诸多挑战,如探测器的灵敏度低、分辨率有限,无法进行动态显像,难以显示和识别小病灶,显像剂剂量较大,成像时间长,患者易发生位移等。应用碲锌镉(cadmium-zinc-telluride,CZT)晶体作为探测器的心脏专用SPECT(简称CZT-SPECT)采用新的半导体探测器、准直器和重建算法,达到了降低显像剂剂量、缩短采集时间、改善图像质量和扩展临床应用范围等目的。笔者对CZT-SPECT的临床应用进展进行综述。
碲锌镉心脏专用SPECT的临床应用进展
The clinical progress of cadmium-zinc-telluride-based dedicated cardiac SPECT cameras
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摘要: 心肌灌注显像在已知或可疑冠状动脉疾病患者的诊疗过程中发挥着重要作用,应用碲锌镉探测器的心脏专用SPECT的分辨率和灵敏度均得到提高,达到了降低显像剂剂量、缩短采集时间、改善图像质量和扩展临床应用范围等目的。笔者对碲锌镉心脏专用SPECT的临床应用进展进行综述。
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关键词:
- 冠心病 /
- 心肌灌注显像 /
- 体层摄影术,发射型计算机,单光子 /
- 体层摄影术,X线计算机 /
- 碲锌镉
Abstract: Myocardial perfusion imaging plays an important role in the diagnosis and treatment of patients with known or suspected coronary artery disease. The cadmium-zinc-telluride (CZT)-based dedicated cardiac SPECT (called CZT-SPECT) with high resolution and photon sensitivity reduces radiation exposure and imaging time while improving image quality and enhancing the value of SPECT myocardial perfusion imaging in clinical practice. The review elaborates the clinical progress of CZT-SPECT. -
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