[1] Yu HS, Song AQ, Fei CH, et al.  Effects of low dose radiation on tumor apoptosis, cell cycle and apoptosis-related protein Bcl-2 in tumor-bearing mice[J]. Chin-Ger J Clin Oncol, 2005, 4(2): 89-92.   doi: 10.1007/S10330-004-0276-2
[2] Wu CL, Tian B, Qu XH, et al.  MicroRNAs play a role in chondrogenesis and osteoarthritis (Review)[J]. Int J Mol Med, 2014, 34(1): 13-23.   doi: 10.3892/ijmm.2014.1743
[3] Piotto C, Biscontin A, Millino C, et al.  Functional validation of miRNAs targeting genes of DNA double-strand break repair to radiosensitize non-small lung cancer cells[J]. Biochim Biophys Acta (BBA)-Gene Regul Mech, 2018, 1861(12): 1102-1118.   doi: 10.1016/j.bbagrm.2018.10.010
[4] Wang LJ, Li NN, Xu SJ, et al.  A new and important relationship between miRNA-147a and PDPK1 in radiotherapy[J]. J Cell Biochem, 2018, 119(4): 3519-3527.   doi: 10.1002/jcb.26523
[5] Chu YC, Hu XL, Wang GF, et al.  Downregulation of miR-136 promotes the progression of osteosarcoma and is associated with the prognosis of patients with osteosarcoma[J]. Oncol Lett, 2019, 17(6): 5210-5218.   doi: 10.3892/ol.2019.10203
[6] Lan FM, Yue X, Ren G, et al.  miR-15a/16 enhances radiation sensitivity of non-small cell lung cancer cells by targeting the TLR1/NF-κB signaling pathway[J]. Int J Radiat Oncol Biol Phys, 2015, 91(1): 73-81.   doi: 10.1016/j.ijrobp.2014.09.021
[7]

Zhou L, Chen JH, Li ZZ, et al. Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27.3 associate with clear cell renal cell carcinoma[J/OL]. PLoS One, 2010, 5(12): e15224[2020-11-29]. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015224. DOI: 10.1371/journal.pone.0015224.

[8]

Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2[J/OL]. Genome Biol, 2014, 15(12): 550[2020-11-29]. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-014-0550-8. DOI: 10.1186/s13059-014-0550-8.

[9] Zhang Z, Wu H, Zhou H, et al.  Identification of potential key genes and high-frequency mutant genes in prostate cancer by using RNA-Seq data[J]. Oncol Lett, 2018, 15(4): 4550-4556.   doi: 10.3892/ol.2018.7846
[10]

Wen M, Shen Y, Shi SH, et al. miREvo: an integrative microRNA evolutionary analysis platform for next-generation sequencing experiments[J/OL]. BMC Bioinformatics, 2012, 13(1): 140[2020-11-29]. https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-13-140. DOI: 10.1186/1471-2105-13-140.

[11] Kanehisa M, Araki M, Goto S, et al.  KEGG for linking genomes to life and the environment[J]. Nucleic Acids Res, 2008, 36(Datebase issue): D480-D484.   doi: 10.1093/nar/gkm882
[12] Terradas M, Martín M, Repullès J, et al.  Distinct sets of lncRNAs are differentially modulated after exposure to high and low doses of X rays[J]. Radiat Res, 2016, 186(6): 549-558.   doi: 10.1667/rr14377.1
[13] Osipov A N, Buleeva G, Arkhangelskaya E, et al.  In vivo γ-irradiation low dose threshold for suppression of DNA double strand breaks below the spontaneous level in mouse blood and spleen cells[J]. Mutat Res/Genet Toxicol Environ Mutagen, 2013, 756(1/2): 141-145.   doi: 10.1016/j.mrgentox.2013.04.016
[14] 刘淑春, 赵文举, 吕喆, 等.  低剂量辐射诱导EL-4淋巴瘤细胞凋亡及细胞周期进程适应性反应的剂量率效应[J]. 吉林大学学报(医学版), 2008, 34(1): 24-27.   doi: 10.3969/j.issn.1671-587X.2008.01.006
Liu SC, Zhao WJ, Lyu Z, et al.  Dose-rate effect of adaptive response of apoptosis and cell cycle progression induced by low-dose ionizing radiation in EL-4 lymphoma cells in vitro[J]. J Jilin Univ: Med Ed, 2008, 34(1): 24-27.   doi: 10.3969/j.issn.1671-587X.2008.01.006
[15]

Chen N, Wu LJ, Yuan H, et al. ROS/autophagy/Nrf2 pathway mediated low-dose radiation induced radio-resistance in human lung adenocarcinoma A549 cell[J/OL]. Int J Biol Sci, 2015, 11(7): 833−844[2020-11-29]. https://www.ijbs.com/v11p0833.htm. DOI: 10.7150/ijbs.10564.

[16] Terashima S, Hosokawa Y, Tsuruga E, et al.  Impact of time interval and dose rate on cell survival following low-dose fractionated exposures[J]. J Radiat Res, 2017, 58(6): 782-790.   doi: 10.1093/jrr/rrx025
[17] Wakeford R, Tawn EJ.  The meaning of low dose and low dose-rate[J]. J Radiol Prot, 2010, 30(1): 1-3.   doi: 10.1088/0952-4746/30/1/E02
[18] Ye J, Xiao X, Han Y, et al.  MiR-3662 suppresses cell growth, invasion and glucose metabolism by targeting HK2 in hepatocellular carcinoma cells[J]. Neoplasma, 2020, 67(4): 773-781.   doi: 10.4149/neo_2020_190730n689
[19] Powrózek T, Krawczyk P, Kowalski DM, et al.  Plasma circulating microRNA-944 and microRNA-3662 as potential histologic type-specific early lung cancer biomarkers[J]. Transl Res, 2015, 166(4): 315-323.   doi: 10.1016/j.trsl.2015.05.009
[20]

Chang H, Liu YH, Wang LL, et al. MiR-182 promotes cell proliferation by suppressing FBXW7 and FBXW11 in non-small cell lung cancer[J/OL]. Am J Transl Res, 2018, 10(4): 1131−1142[2020-11-29]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934572.

[21] 陈光朋, 付万垒, 杨坤富, 等.  miR-182调控RECK信号通路在非小细胞肺癌进展中的作用[J]. 解放军医学杂志, 2015, 40(4): 309-314.   doi: 10.11855/j.issn.0577-7402.2015.04.11
Chen GP, Fu WL, Yang KF, et al.  Effect of miR-182 in non small cell lung cancer via regulating the RECK signaling pathway[J]. Med J Chin PLA, 2015, 40(4): 309-314.   doi: 10.11855/j.issn.0577-7402.2015.04.11
[22]

Masliah-Planchon J, Garinet S, Pasmant E. RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action[J/OL]. Oncotarget, 2016, 7(25): 38892−38907[2020-11-29]. https://www.oncotarget.com/article/6476/text. DOI: 10.18632/oncotarget.6476.

[23] Drosten M, Barbacid M.  Targeting the MAPK pathway in KRAS-Driven tumors[J]. Cancer Cell, 2020, 37(4): 543-550.   doi: 10.1016/j.ccell.2020.03.013
[24]

Huang T, Yin L, Wu J, et al. MicroRNA-19b-3p regulates nasopharyngeal carcinoma radiosensitivity by targeting TNFAIP3/NF-κB axis[J/OL]. J Exp Clin Cancer Res, 2016, 35(1): 188[2020-11-29]. https://jeccr.biomedcentral.com/articles/10.1186/s13046-016-0465-1. DOI: 10.1186/s13046-016-0465-1.

[25] Dent P, Yacoub A, Fisher PB, et al.  MAPK pathways in radiation responses[J]. Oncogene, 2003, 22(37): 5885-5896.   doi: 10.1038/sj.onc.1206701
[26]

Mutlu M, Saatci Ö, Ansari SA, et al. miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer[J/OL]. Sci Rep, 2016, 6: 32541[2020-11-29]. https://www.nature.com/articles/srep32541. DOI: 10.1038/srep32541.

[27] Hagan M, Wang L, Hanley JR, et al.  Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest[J]. Radiat Res, 2000, 153(4): 371-383.   doi: 10.1667/0033-7587(2000)153[0371:irimap]2.0.co;2
[28] Tian XQ, Geng J, Zheng Q, et al.  Single high dose irradiation induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cells through the Ras/Raf/MEK/ERK pathways[J]. Int J Radiat Biol, 2020, 96(6): 740-747.   doi: 10.1080/09553002.2020.1694188