[1] |
Fletcher L, Cheng Y, Muschel RJ. Abolishment of the Tyr-15 inhibitory phosphorylation site on cdc2 reduces the radiation-induced G(2) delay, revealing a potential checkpoint in early[J]. Cancer Res, 2002, 62(1):241-250.
|
[2] |
Luo Y, Chen Z, Han EK, et al. Blocking Chk1 expression induces apoptosis and abrogates the G2 checkpoint mechanism[J]. Neoplasia, 2001, 3(5):411-419.
|
[3] |
Jackson JR, Roshak A, Winkler JD, et al. An indolocarbazole inhibitor of human checkpoint kinase (Chkl) abrogates cell cycle arrest caused by DNA damage[J]. Cancer Res, 2000, 60(3):566-572.
|
[4] |
Ding Z, Parchment RE, LoRusso PM, et al. The investigational new drug XK469 induces G(2)-M cell cycle arrest by p53-dependent and -independent pathways[J]. Clin Cancer Res, 2001, 7(11):3336-3342.
|
[5] |
Hu BC, Wang X, Wang Y, et al. The radioresistance to killing of A1-5 cells derives from activation of the Chk1 pathway[J]. Biol Chem, 2001, 276(21):17693-17698.
|
[6] |
Oe T, Nakajo N, Katsuragi Y, et al. Cytoplasmic occurrence of the Chk1/Cdc25 pathway and regulation of Chk1 in Xenopus oocytes[J]. Dev Biol, 2001, 229(1):250-261.
|
[7] |
Atsushi H, Kong YY, Shuhei M, et al. DNA damage-induced activation of p53 by the checkpoint kinase Chk2[J]. Science, 2000, 287:1824-1827.
|
[8] |
Robert SW, Shuhei M, Stephen JE, et al. Husl acts upstream of chk1 in a mammalian DNA damage response pathway[J]. Current Biol, 2002, 12(1):73-77.
|
[9] |
Matsui F, Tsuchida Y, Keng PC. Effects of p53 mutations on cellular sensitivity to ionizing radiation[J]. Am J Clin Oncol, 2001, 24(5):486-490.
|
[10] |
Taylor WR, Atark GR, Galante J, et al. p130/E2F4 binds to and represses the cdc2 promoter in response to p53[J]. Biol Chem, 2001, 276(3):1998-2006.
|
[11] |
Jin S, Antinore MJ, Lung FD, et al. The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression[J]. Biol Chem, 2000, 275(22):16602-16608.
|
[12] |
Lee SL, Tian Hui, Faje AT, et al. Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways[J]. Neoplasia, 2002, 4(2):171-180.
|
[13] |
Gottifredi V, Karni SO, Shieh SS, et al. p53 down-regnlates CHK1 through p21 and the retinoblastoma protein[J]. Mol Cell Biol, 2001, 21(4):1066-1076.
|