<sup>99</sup>Tc<sup>m</sup>-MDP骨显像胸部异常放射性摄取的原因分析

任佳忠; 李永梅; 刘岩; 杨国仁; 任佳忠; 李永梅; 刘岩; 杨国仁

doi:10.3760/cma.j.issn.1673-4114.2016.06.011

[1]

支修益, 石远凯, 于金明.中国原发性肺癌诊疗规范(2015年版)[J].中华肿瘤杂志, 2015, 37(1):67-78. DOI:10.3760/cma.j.issn.0253-3766.2015.01.014.
Zhi XY, Shi YK, Yu JM.Standards for the diagnosis and treatment of primary lung cancer(2015 version) in China[J].Chin J Oncol, 2015, 37(1):67-78. doi: 10.3760/cma.j.issn.0253-3766.2015.01.014

[2]

张芬茹, 许建林, 周建平, 等.肿瘤患者骨外软组织摄取骨显像剂的临床意义[J].中国医学影像技术, 2007, 23(7):1076-1079. DOI:10.3321/j.issn:1003-3289.2007.07.037.
Zhang FR, Xu JL, Zhou JP, et al.Clinical significance of nonosseous soft tissue uptake of bone trace in cancer patients[J].Chin J Med Imaging Technol, 2007, 23(7):1076-1079. doi: 10.3321/j.issn:1003-3289.2007.07.037

[3]

Kim SJ, Choi JA, Lee SH, et al.Imaging finding of extrapulmonary metastases of osteosarcoma[J].Clin Imaging, 2004, 28(4):291-300. DOI:10.1016/S0899-7071(03)00206-7.

[4]

Andreas KB, Stephan N, Sibylle Z, et al.SPECT/CT[J].J Nucl Med, 2008, 49(3):1305-1319. DOI:10.2967/jnumed.107.050195.

[5]

石洪成.SPECT/CT诊断操作规范与临床应用[M].上海:上海科技出版社, 2015:56-78.

Shi HC.Procedure guideline and clinical application of hybrid SPECT/diagnostic CT[M].Shanghai:Shanghai Scientific and Technical Publishers, 2015:56-78.

[6]

谢良骏, 曾凤伟, 张峰, 等.核素全身骨显像鉴别诊断肋脊关节骨转移瘤[J].中国介入影像与治疗学, 2014, 11(3):153-156. DOI:10.13929/j.1672-8475.2014.03.004.
Xie LJ, Zeng FW, Zhang F, et al.Radionuclide whole body bone imaging in differential diagnosis of costovertebral joint metastases[J].Chin J Interv Imaging Ther, 2014, 11(3):153-156. doi: 10.13929/j.1672-8475.2014.03.004

[7]

黄定德, 李前伟, 厉红民, 等.放射性核素骨显像不典型表现248例临床分析[J].重庆医学, 2005, 34(8):1137-1138. DOI:1671-8348(2005)08-1137-02.
Huang DD, Li QW, Li HM, et al.Clinical analysis of radionuclide whole bone imaging of untypical lesions in 248 cases[J].Chongqing Med J, 2005, 34(8):1137-1138. doi: 10.3969/j.issn.1671-8348.2005.08.010

[8]

Gunay EC, Erdogan A, Apaydin D.Unusual extraosseous tumoral accumulation of ^99mTc-MDP in non-Hodgkin's lymphoma in two cases[J].Rev Esp Med Nucl, 2011, 30(3):162-164. DOI:10.1016/j.remn.2010.04.012.

[9]

李晶, 张建, 杨小丰, 等.^99mTc-MDP骨显像在多发性骨髓瘤与多发性骨转移瘤鉴别诊断中的应用价值[J].新疆医学, 2014, 44(7):52-54.
Li J, Zhang J, Yang XF, et al.Value of ^99mTc-MDP bone imaging in differential diagnosis of multiple myeloma and multiple bone metastases[J].Xinjiang Med J, 2014, 44(7):52-54.

[10]

张一秋, 石洪成, 顾宇参, 等.SPECT/CT骨显像对肺癌骨转移诊断的增益价值[J].中华核医学杂志, 2011, 31(4):219-222. DOI:10.3760/cma.j.issn.0253-9780.2011.04.002.
Zhang YQ, Shi HC, Gu YC, et al.The added diagnostic value of SPECT/CT imaging for bone metastases from lung cancer[J].Chin J Nucl Med, 2011, 31(4):219-222. doi: 10.3760/cma.j.issn.0253-9780.2011.04.002

[11]

张倩, 修雁, 石洪成, 等.核素骨显像与骨质疏松症的诊断[J].中华骨质疏松与骨矿盐疾病杂志, 2012, 5(4):1674-2591. DOI:10.3969/j.issn.1674-2591.2012.04.013.
Zhang Q, Xiu Y, Shi HC, et al.Value of radionuclide bone imaging in diagnosis of osteoporosis[J].Chin J Osteoporosis Bone Miner Res, 2012, 5(4):1674-2591. doi: 10.3969/j.issn.1674-2591.2012.04.013

[12]

孔西建, 刘玉珂, 李盈盈, 等.瘤源性骨软化症的影像学诊断[J].中国医学影像学杂志, 2014, 22(8):1005-5185. DOI:10.3969/j.issn.1005-5185.2014.08.019.
Kong XJ, Liu YK, Li YY, et al.Imaging diagnosis of tumor-induced osteomalacia[J].Chin J Med Imaging, 2014, 22(8):1005-5185. doi: 10.3969/j.issn.1005-5185.2014.08.019

[13]

程旭, 李永军, 徐兆强, 等.^99mTc-MDP全身骨扫描在肾性骨病中的显像特点探讨[J].南京医科大学学报(自然科学版), 2014, 34(9):1260-1263. DOI:10.7655/NYDXBNS20140923.
Cheng X, Li YJ, Xu ZQ, et al.To investigate the imaging features of renal osteodystrophy in bone ^99mTc-MDP scan[J].J Nanjing Med Univ(Nat Sci), 2014, 34(9):1260-1263. doi: 10.7655/NYDXBNS20140923

[14]

张连娜, 杨芳, 冯瑾.甲旁亢与骨软化症的骨显像对比分析[J].中国临床医学影像杂志, 2015, 26(9):663-666. DOI:1008-1062(2015)09-0663-04.
Zhang LN, Yang F, Feng J.Comparative analysis of bone imaging features of primary hyperparathyroidism and osteomalacia[J].J China Clin Med Imaging, 2015, 26(9):663-666.

[15]

Agrawal A, Purandare N, Sridhar E, et al.Imaging findings in a rare case of Extra-Articular chondrocalcinosis[J].Clin Nucl Med, 2012, 37(2):184-187. DOI:10.1097/RLU.0b013e31823ea13e.

[16]

Cerci SS, Suslu H, Cerci C, et al.Different findings in Tc-99m MDP bone scintigraphy of patients with sickle cell disease:report of three cases[J].Ann Nucl Med, 2007, 21(5):311-314. DOI:10.1007/s12149-007-0025-z.

[17]

杨中, 徐海青, 吴边, 等.^99mTc-MDP骨显像与X线、CT联合诊断SAPHO综合征[J].热带病与寄生虫学, 2014, 12(4):235-253. DOI:10.3969/j.issn.1672-2302.2014.04.015.
Yang Z, Xu HQ, Wu B, et al.Combined diagnosis of SAPHO syndrome by 99mTC-MDP bone imaging, X-ray and CT[J].J Trop Dis Parasitol, 2014, 12(4):235-253. doi: 10.3969/j.issn.1672-2302.2014.04.015

[18]

髙瞻.核素骨显像在肿瘤临床中的应用[J].东南国防医药, 2009, 11(6):523-526. DOI:1672-271X(2009)06-0523-04.
Gao Z. Application of nuclide bone imaging in clinical cancer diagnosis[J].Military Med J Southeast China, 2009, 11(6):523-526.

[19]

王娜, 刘生, 蒋宁一, 等.多骨型骨纤维异常增殖症核素骨显像误诊为Paget病1例[J].医学影像学杂志, 2008, 18(2):1006-9011. DOI:1006-9011(2008)02-0186-01.
Wang N, Liu S, Jiang NY, et al.Polyostotic fibrous dysplasia misdiagnosed as Paget disease by radionuclide bone imaging:a case report[J].J Med Imaging, 2008, 18(2):1006-9011.

[20]

Nagano S, Yokouchi M, Nagayoshi RA, et al.Paget disease of bone in Japanese patients:a report of three cases[J].J Orthop Surg, 2013, 21(3):375-379.

[21]

Shimoyama Y, Kusano M, Shimoda Y, et al.Paget's disease of bone resembling bone metastasis from gastric cancer[J].Clin J Gastroenterol, 2011, 4(4):207-211. DOI:10.1007/s12328-011-0230-0.

[22]

孙达.放射性核素骨显像[M].浙江:浙江大学出版社, 2000:104.

Sun D.Radionuclide bone imaging[M].Zhejiang:Zhejiang University Press, 2000:104.

[23]

谢敬慧, 张延军, 张欣, 等.骨外组织摄取骨显像剂的所见及临床意义探讨(附497例报告)[J].中国临床医学影像杂志, 2006, 17(10):588-591. DOI:10.3969/j.issn.1008-1062.2006.10.016.
Xie JH, Zhang YJ, Zhang X, et al.The appearances and evaluation of ⁹⁹Tc^m-MDP accumulation in non-osseous tissue:report of 497 cases[J].J China Clin Med Imaging, 2006, 17(10):588-591. doi: 10.3969/j.issn.1008-1062.2006.10.016

[24]

Eagel BA, Stier S, Wakem C.Non-osseous bone scan abnormlities in multiple myeloma associated with hypercalcemia[J].Clin Nucl Med, 1988, 13(12):869-873. doi: 10.1097/00003072-198812000-00004

[25]

Marwah A, Kumar R, Dasan B, et al.Soft tissue uptake of Tc-99m-MDP in acute lymphoblastic leukemia[J].Clin Imaging, 2002, 26(3):206-208. DOI:10.1016/S0899-7071(01)00384-9.

[26]

Ju HU, Seo KW, Jegal Y, et al.A case of alveolar soft part sarcoma of the pleura[J].J Korean Med Sci, 2013, 28(2):331-335. DOI:10.3346/jkms.2013.28.2.331.

[27]

Soundararajan R, Naswa N, Sharma P, et al.SPECT-CT for characterization of extraosseous uptake of ^99mTc-methylene diphosphonate on bone scintigraphy[J].Diagn Interv Radiol, 2013, 19(5):405-410. DOI:10.5152/dir.2013.054.

[28]

Quoix E, Chenard MP, Orion B, et al.A left pleural effusion with a calcified tumoral mass and left hemithoracic uptake on bone scan[J].Lung Cancer, 2001, 32(2):203-205. DOI:10.1016/S0169-5002(00)00234-8.

[29]

James B, Chandler NC, Quarless SA.Extraosseous uptake of Tc-99m MDP along the radiation therapy port for recurrent squamous cell carcinoma of the lung[J].Clin Nucl Med, 2005, 30(8):555-557. DOI:10.1097/01.rlu.0000170042.33387.30.

[30]

马超, 匡安仁, 左书耀, 等.放射性核素骨显像骨外异常放射性浓聚影的原因[J].中华核医学杂志, 2006, 26(5):2095-2848.
Ma C, Kuang AR, Zuo SY, et al.Reason of radioactive concentration in bone of radionuclide bone imaging[J].Chin J Nucl Med, 2006, 26(5):2095-2848.

[31]

Siegel ME, Walker WJ, Campbell JL.Accumulation of Tc-99m-diphosphonate in malignant pleural effusions:detection an verification[J].J Nucl Med, 1975, 16(10):883-885.

[32]

Kawase T, Fujii H, Nakahara TA, et al.Intense accumulation of Tc-99m MDP in pericardial metastasis from breast cancer[J].Clin Nucl Med, 2009, 34(3):173-174. DOI:10.1097/RLU.0b013e31819672b9.

[33]

Li L, Kuang A, Sheng S, et al.Tc-99m MDP uptake in retroperitoneal malignant peripheral nerve sheath tumor and its metastases[J].Clin Nucl Med, 2006, 31(1):44-45.

[34]

Barai S, Kuamr R, Haloi AK, et al.Bone scan demonstrating metastasis to the breast from an ovarian carcinoma and a review of the literature[J].Clin Nucl Med, 2004, 29(3):167-170.

[35]

金星, 林爱珠, 郑石芳.肿瘤患者核素骨显像骨外软组织浓聚的分析[J].中国临床医学影像杂志, 2000, 11(5):332-334. DOI:10.3969/j.issn.1008-1062.2000.05.011.
Jin X, Lin AZ, Zheng SF.Analysis of concentration of soft tissues outside bone on nuclide imaging of cancer patients[J].J China Clin Med Imaging, 2000, 11(5):332-334. doi: 10.3969/j.issn.1008-1062.2000.05.011

[36]

Shen YY, Wu YC, Kao CH, et al.Huge primary soft tissue sarcoma of the breast on bone scan[J].Clin Nucl Med, 2014, 39(1):99-101. DOI:10.1097/RLU.0000000000000246.

[37]

Palaniswamy SS, Padma S, Harish V, et al.Hypercalcemia with extraosseous MDP uptake in a bone scan as initial presentation in a case of cutaneous T-cell lymphoma[J].J Cancer Res Ther, 2011, 7(1):72-74. DOI:10.4103/0973-1482.80474.