<sup>18</sup>F-FLT联合<sup>18</sup>F-FDG诊断高分化肝癌一例

张威; 许国辉; 程祝忠; 姚玉唐; 何发伟; 李勇; 罗红兵; 张威; 许国辉; 程祝忠; 姚玉唐; 何发伟; 李勇; 罗红兵

doi:10.3760/cma.j.issn.1673-4114.2019.04.014

[1]

唐平, 孟兆娣. 复发性肝内胆管细胞癌的治疗现状[J]. 实用医学杂志, 2017, 33(4): 657-660. doi: 10.3969/j.issn.1006-5725.2017.04.044
Tang P, Meng ZD. Current status of treatment for recurrent intrahepatic cholangiocarcinoma[J]. J Pract MedJ Pract Med, 2017, 33(4): 657-660. doi: 10.3969/j.issn.1006-5725.2017.04.044

[2]

中华人民共和国卫生和计划生育委员会医政医管局. 原发性肝癌诊疗规范(2017年版)[J]. 中华消化外科杂志, 2017, 16(7): 635-647. doi: 10.3760/cma.j.issn.1673-9752.2017.07.001
Medical Administration of the Health and Family Planning Commission of the People's Republic of China. Standardization of diagnosis and treatment for hepatocellular carcinoma (2017 edition)[J]. Chin J Digest SurgChin J Digest Surg, 2017, 16(7): 635-647. doi: 10.3760/cma.j.issn.1673-9752.2017.07.001

[3]

冯智超, 朱文卫, 刘倩云, 等. 动脉增强分数定量彩图对肝脏局灶性结节增生与肝细胞癌的鉴别诊断价值[J]. 临床放射学杂志, 2017, 36(2): 231-235. doi: 10.13437/j.cnki.jcr.2017.02.020
Feng ZC, Zhu WW, Liu QY, et al. Differential Diagnosis Value of Quantitative Color Mapping of the Arterial Enhancement Fraction between Hepatic Focal Nodular Hyperplasia and Hepatocellular Carcinoma[J]. J Clin RadiolJ Clin Radiol, 2017, 36(2): 231-235. doi: 10.13437/j.cnki.jcr.2017.02.020

[4]

张峰, 谢良骏, 曹素娥, 等. ¹⁸F-FDG PET/CT延迟显像在原发性肝癌诊断中的应用价值[J]. 中华肝脏外科手术学电子杂志, 2017, 6(4): 324-327. doi: 10.3877/cma.j.issn.2095-3232.2017.04.020
Zhang F, Xie LJ, Cao SE, et al. Application value of ¹⁸F-FDG PET/CT delayed imaging in diagnosis of primary liver cancer[J]. Chin J Hepat SurgChin J Hepat Surg, 2017, 6(4): 324-327. doi: 10.3877/cma.j.issn.2095-3232.2017.04.020

[5]

尚玉琨, 谢明萱. PET在肝脏肿瘤诊断中的应用及研究进展[J]. 中华国际医学杂志, 2002, 2(1): 76-78.
Shang YK, Xie MX. The application and research progress of PET in the diagnosis of liver tumors[J]. Chin J Int MedChin J Int Med, 2002, 2(1): 76-78.

[6]

王晓燕, 张祥松, 陈志丰, 等. ¹⁸F-FDG PET/CT及增强CT诊断原发性肝癌及肝癌术后复发的价值[J]. 中华核医学杂志, 2010, 30(1): 15-18. doi: 10.3760/cma.j.issn.0253-9780.2010.01.004
Wang XY, Zhang XS, Chen ZF, et al. The diagnostic value of comparison of ¹⁸F-FDG PET/CT with contrast-enhanced CT in detecting primary hepatic carcinoma and postoperative recurrence[J]. Chin J Nucl MedChin J Nucl Med, 2010, 30(1): 15-18. doi: 10.3760/cma.j.issn.0253-9780.2010.01.004

[7]

江骁, 王潇雄, 陆皓, 等. CFN-MPS-200模块自动化制备¹⁸F-FLT及其质量控制与生物评价[J]. 四川大学学报: 医学版, 2017, 48(2): 295-298. doi: 10.13464/j.scuxbyxb.2017.02.026
Jiang X, Wang XX, Lu H, et al. Quality Control and Biological Assessment of Automated Synthesized 3'-deoxy-3'-¹⁸F-fluorothymidine using CFN-MPS-200 Module[J]. J Sichuan Univ: Med EdJ Sichuan Univ: Med Ed, 2017, 48(2): 295-298. doi: 10.13464/j.scuxbyxb.2017.02.026

[8]

路丽彦, 姜磊, 高云朝, 等. ¹⁸F-FLT与¹⁸F-FDG评估白血病荷瘤裸鼠模型肿瘤增殖的研究[J]. 上海交通大学学报: 医学版, 2012, 32(10): 1312−1315. DOI: 10.3969/j.issn.1674−8115.2012.10.007.

Lu LY, Jiang L, Gao YC, et al. Application of ¹⁸F-FLT and ¹⁸F-FDG in evaluation of tumor proliferation of nude mouse models of leukemia[J]. J Shanghai Jiaotong Univ: Med Ed, 2012, 32(10): 1312−1315. DOI: 10.3969/j.issn.1674−8115.2012.10.007.

[9]

江茂情, 吴华. ¹⁸F-FDG和¹⁸F-FLT PET-CT在肿瘤非手术治疗早期疗效评价中的应用[J]. 国际放射医学核医学杂志, 2012, 36(6): 339-343. doi: 10.3760/cma.j.issn.1673-4114.2012.06.005
Jiang MQ, Wu H. ¹⁸F-FDG and ¹⁸F-FLT PET-CT in evaluation of the early response of malignant tumors after different therapies[J]. Int J Radiol Med Nucl MedInt J Radiol Med Nucl Med, 2012, 36(6): 339-343. doi: 10.3760/cma.j.issn.1673-4114.2012.06.005

[10]

Torizuka T, Tamaki N, Inokuma T, et al. Value of fluorine-18-FDG-PET to monitor hepatocellular carcinoma after interventional therapy[J]. J Nucl MedJ Nucl Med, 1994, 35(12): 1965-1969.

[11]

Anderson GS, Brinkmann F, Soulen MC, et al. FDG positron emission tomography in the surveillance of hepatic tumors treated with radiofrequency ablation[J]. Clin Nucl MedClin Nucl Med, 2003, 28(3): 192-197. doi: 10.1097/01.RLU.0000053530.95952.FD

[12]

Danve A, O'Dell J. The Role of ¹⁸F Fluorodeoxyglucose Positron Emission Tomography Scanning in the Diagnosis and Management of Systemic Vasculitis[J]. Int J Rheum DisInt J Rheum Dis, 2015, 18(7): 714-724. doi: 10.1111/1756-185X.12713

[13]

李立伟, 金泉, 马璐娜, 等. 肝癌经动脉栓塞化疗后FDG PET显像的临床价值——附10例FDG PET和CT结果对照[J]. 中国医学影像技术, 2001, 17(11): 1074-1075. doi: 10.3321/j.issn:1003-3289.2001.11.020
Li LW, Jin Q, Ma LN, et al. Clinical Value of FDG PET Imaging in Monitoring Hepatocellular Carcinoma after Chemoembolization Compared FDG PET with CT in 10 Cases[J]. Chin Med Imag TechnolChin Med Imag Technol, 2001, 17(11): 1074-1075. doi: 10.3321/j.issn:1003-3289.2001.11.020

[14]

何玉林, 王雪梅, 包宝亮. ¹⁸F-FLT合成及其在PET/CT显像中的应用[J]. 内蒙古医学院学报, 2010, 32(2): 95-98. doi: 10.3969/j.issn.1004-2113.2010.02.005
He YL, Wang XM, Bao BL. THE SYNTHESIS AND APPLICATION OF ¹⁸F-FLT IN PET/CT IMAGING[J]. Acta Acad Med Nei MongolActa Acad Med Nei Mongol, 2010, 32(2): 95-98. doi: 10.3969/j.issn.1004-2113.2010.02.005

[15]

王甜甜, 赵晋华. ¹⁸F-FLT增殖显像机制及前期临床研究[J]. 国际放射医学核医学杂志, 2012, 36(1): 8-12. doi: 10.3760/cma.j.issn.1673-4114.2012.01.002
Wang TT, Zhao JH. The basis of ¹⁸F-3'-deoxy-3'-L-fluorothymidine as a proliferation tracer and preclinical study[J]. Int J Radiol Med Nucl MedInt J Radiol Med Nucl Med, 2012, 36(1): 8-12. doi: 10.3760/cma.j.issn.1673-4114.2012.01.002

[16]

陈晓婷, 赵鑫, 高振华, 等. 非小细胞肺癌¹⁸F-FLT PET显像结果与肿瘤细胞高增殖区的一致性探讨[J]. 山东医药, 2016, 56(6): 45-47. doi: 10.3969/j.issn.1002-266X.2016.06.016
Chen XT, Zhao X, Gao ZH, et al. Consistency between ¹⁸F-FLT PET imaging results and hyperproliferative regions of tumor cells[J]. Shandong MedShandong Med, 2016, 56(6): 45-47. doi: 10.3969/j.issn.1002-266X.2016.06.016

[17]

陈雷, 柳曦. ¹⁸F-FDG和¹⁸F-FLT的正电子发射断层显像对肿瘤放化疗疗效评价的实验研究[J]. 中国医药导报, 2013, 10(18): 41-43. doi: 10.3969/j.issn.1673-7210.2013.18.014
Chen L, Liu X. Experimental research of ¹⁸F-FDG and ¹⁸F-FLT PET in efficient evaluation of tumor chemotherapy[J]. Chin Med JChin Med J, 2013, 10(18): 41-43. doi: 10.3969/j.issn.1673-7210.2013.18.014

[18]

Buck AK, Halter G, Schirrmeister H, et al. Imaging Proliferation in Lung Tumors with PET: ¹⁸F-FLT Versus ¹⁸F-FDG[J]. J Nucl MedJ Nucl Med, 2003, 44(9): 1426-1431.

[19]

Troost EGC, Bussink J, Hoffmann AL, et al. ¹⁸F-FLT PET/CT for Early Response Monitoring and Dose Escalation in Oropharyngeal Tumors[J]. J Nucl MedJ Nucl Med, 2010, 51(6): 866-874. doi: 10.2967/jnumed.109.069310

[20]

Dittmann H, Dohmen BM, Paulsen F, et al. [¹⁸F]FLT PET for diagnosis and staging of thoracic tumours[J]. Eur J Nucl Med Mol ImagEur J Nucl Med Mol Imag, 2003, 30(10): 1407-1412. doi: 10.1007/s00259-003-1257-3

[21]

Timmer SAJ, Lubberink M, Germans T, et al. Potential of [¹¹C]acetate for measuring myocardial blood flow: Studies in normal subjects and patients with hypertrophic cardiomyopathy[J]. J Nucl CardiolJ Nucl Cardiol, 2010, 17(2): 264-275. doi: 10.1007/s12350-009-9181-y

[22]

Liu D, Khong PL, Gao YM, et al. Radiation Dosimetry of Whole-Body Dual-Tracer ¹⁸F-FDG and ¹¹C-Acetate PET/CT for Hepatocellular Carcinoma[J]. J Nucl Med Off Publ Soc Nucl MedJ Nucl Med Off Publ Soc Nucl Med, 2016, 57(6): 907-912. doi: 10.2967/jnumed.115.165944

[23]

霍力, 党永红, 崔瑞雪, 等. ¹¹C-乙酸盐PET双时相显像鉴别诊断肝原发肿瘤[J]. 中华核医学与分子影像杂志, 2014, 34(2): 96-99. doi: 10.3760/cma.j.issn.2095-2848.2014.02.004
Huo L, Dang YH, Cui RX, et al. Detection of primary hepatoma with early and routine ¹¹C-acetate PET imaging[J]. Chin J Nucl Med Mol ImagChin J Nucl Med Mol Imag, 2014, 34(2): 96-99. doi: 10.3760/cma.j.issn.2095-2848.2014.02.004

[24]

孙爱君, 任茜, 刘健, 等. ¹¹C-乙酸盐PET和PET/CT在肿瘤显像中的应用[J]. 国际放射医学核医学杂志, 2013, 37(4): 243-247. doi: 10.3760/cma.j.issn.1673-4114.2013.04.013
Sun AJ, Ren X, Liu J, et al. The application of ¹¹C-acetate PET and PET-CT for tumors[J]. Int J Radiol Med Nucl MedInt J Radiol Med Nucl Med, 2013, 37(4): 243-247. doi: 10.3760/cma.j.issn.1673-4114.2013.04.013

[25]

Yoo SW, Kim DY, Lee C, et al. Small Bowel Metastasis From Hepatocellular Carcinoma Detected by ¹⁸F-FDG PET/CT But Not by ¹¹C-Acetate PET/CT[J]. Clin Nucl MedClin Nucl Med, 2017, 42(12): 966-967. doi: 10.1097/RLU.0000000000001882

[26]

Li SR, Peck-Radosavljevic M, Ubl P, et al. The value of [¹¹C]-acetate PET and[¹⁸F]-FDG PET in hepatocellular carcinoma before and after treatment with transarterial chemoembolization and bevacizumab[J]. Eur J Nucl Med Mol ImagEur J Nucl Med Mol Imag, 2017, 44(10): 1732-1741. doi: 10.1007/s00259-017-3724-2

[27]

Cheung TT, Ho CL, Lo CM, et al. ¹¹C-acetate and ¹⁸F-FDG PET/CT for clinical staging and selection of patients with hepatocellular carcinoma for liver transplantation on the basis of Milan criteria: surgeon's perspective[J]. J Nucl MedJ Nucl Med, 2013, 54(2): 192-200. doi: 10.2967/jnumed.112.107516

[28]

Mohsen B, Giorgio T, Rasoul ZS, et al. Application of ¹¹C-acetate positron-emission tomography (PET) imaging in prostate cancer: systematic review and meta-analysis of the literature[J]. BJU IntBJU Int, 2013, 112(8): 1062-1072. doi: 10.1111/bju.12279

[1]	唐平, 孟兆娣. 复发性肝内胆管细胞癌的治疗现状[J]. 实用医学杂志实用医学杂志, 2017, 33(4): 657-660. doi: 10.3969/j.issn.1006-5725.2017.04.044 Tang P, Meng ZD. Current status of treatment for recurrent intrahepatic cholangiocarcinoma[J]. J Pract MedJ Pract Med, 2017, 33(4): 657-660. doi: 10.3969/j.issn.1006-5725.2017.04.044
[2]	中华人民共和国卫生和计划生育委员会医政医管局. 原发性肝癌诊疗规范(2017年版)[J]. 中华消化外科杂志中华消化外科杂志, 2017, 16(7): 635-647. doi: 10.3760/cma.j.issn.1673-9752.2017.07.001 Medical Administration of the Health and Family Planning Commission of the People's Republic of China. Standardization of diagnosis and treatment for hepatocellular carcinoma (2017 edition)[J]. Chin J Digest SurgChin J Digest Surg, 2017, 16(7): 635-647. doi: 10.3760/cma.j.issn.1673-9752.2017.07.001
[3]	冯智超, 朱文卫, 刘倩云, 等. 动脉增强分数定量彩图对肝脏局灶性结节增生与肝细胞癌的鉴别诊断价值[J]. 临床放射学杂志临床放射学杂志, 2017, 36(2): 231-235. doi: 10.13437/j.cnki.jcr.2017.02.020 Feng ZC, Zhu WW, Liu QY, et al. Differential Diagnosis Value of Quantitative Color Mapping of the Arterial Enhancement Fraction between Hepatic Focal Nodular Hyperplasia and Hepatocellular Carcinoma[J]. J Clin RadiolJ Clin Radiol, 2017, 36(2): 231-235. doi: 10.13437/j.cnki.jcr.2017.02.020
[4]	张峰, 谢良骏, 曹素娥, 等. ¹⁸F-FDG PET/CT延迟显像在原发性肝癌诊断中的应用价值[J]. 中华肝脏外科手术学电子杂志中华肝脏外科手术学电子杂志, 2017, 6(4): 324-327. doi: 10.3877/cma.j.issn.2095-3232.2017.04.020 Zhang F, Xie LJ, Cao SE, et al. Application value of ¹⁸F-FDG PET/CT delayed imaging in diagnosis of primary liver cancer[J]. Chin J Hepat SurgChin J Hepat Surg, 2017, 6(4): 324-327. doi: 10.3877/cma.j.issn.2095-3232.2017.04.020
[5]	尚玉琨, 谢明萱. PET在肝脏肿瘤诊断中的应用及研究进展[J]. 中华国际医学杂志中华国际医学杂志, 2002, 2(1): 76-78. Shang YK, Xie MX. The application and research progress of PET in the diagnosis of liver tumors[J]. Chin J Int MedChin J Int Med, 2002, 2(1): 76-78.
[6]	王晓燕, 张祥松, 陈志丰, 等. ¹⁸F-FDG PET/CT及增强CT诊断原发性肝癌及肝癌术后复发的价值[J]. 中华核医学杂志中华核医学杂志, 2010, 30(1): 15-18. doi: 10.3760/cma.j.issn.0253-9780.2010.01.004 Wang XY, Zhang XS, Chen ZF, et al. The diagnostic value of comparison of ¹⁸F-FDG PET/CT with contrast-enhanced CT in detecting primary hepatic carcinoma and postoperative recurrence[J]. Chin J Nucl MedChin J Nucl Med, 2010, 30(1): 15-18. doi: 10.3760/cma.j.issn.0253-9780.2010.01.004
[7]	江骁, 王潇雄, 陆皓, 等. CFN-MPS-200模块自动化制备¹⁸F-FLT及其质量控制与生物评价[J]. 四川大学学报: 医学版四川大学学报: 医学版, 2017, 48(2): 295-298. doi: 10.13464/j.scuxbyxb.2017.02.026 Jiang X, Wang XX, Lu H, et al. Quality Control and Biological Assessment of Automated Synthesized 3'-deoxy-3'-¹⁸F-fluorothymidine using CFN-MPS-200 Module[J]. J Sichuan Univ: Med EdJ Sichuan Univ: Med Ed, 2017, 48(2): 295-298. doi: 10.13464/j.scuxbyxb.2017.02.026
[8]	路丽彦, 姜磊, 高云朝, 等. ¹⁸F-FLT与¹⁸F-FDG评估白血病荷瘤裸鼠模型肿瘤增殖的研究[J]. 上海交通大学学报: 医学版, 2012, 32(10): 1312−1315. DOI: 10.3969/j.issn.1674−8115.2012.10.007. Lu LY, Jiang L, Gao YC, et al. Application of ¹⁸F-FLT and ¹⁸F-FDG in evaluation of tumor proliferation of nude mouse models of leukemia[J]. J Shanghai Jiaotong Univ: Med Ed, 2012, 32(10): 1312−1315. DOI: 10.3969/j.issn.1674−8115.2012.10.007.
[9]	江茂情, 吴华. ¹⁸F-FDG和¹⁸F-FLT PET-CT在肿瘤非手术治疗早期疗效评价中的应用[J]. 国际放射医学核医学杂志国际放射医学核医学杂志, 2012, 36(6): 339-343. doi: 10.3760/cma.j.issn.1673-4114.2012.06.005 Jiang MQ, Wu H. ¹⁸F-FDG and ¹⁸F-FLT PET-CT in evaluation of the early response of malignant tumors after different therapies[J]. Int J Radiol Med Nucl MedInt J Radiol Med Nucl Med, 2012, 36(6): 339-343. doi: 10.3760/cma.j.issn.1673-4114.2012.06.005
[10]	Torizuka T, Tamaki N, Inokuma T, et al. Value of fluorine-18-FDG-PET to monitor hepatocellular carcinoma after interventional therapy[J]. J Nucl MedJ Nucl Med, 1994, 35(12): 1965-1969.
[11]	Anderson GS, Brinkmann F, Soulen MC, et al. FDG positron emission tomography in the surveillance of hepatic tumors treated with radiofrequency ablation[J]. Clin Nucl MedClin Nucl Med, 2003, 28(3): 192-197. doi: 10.1097/01.RLU.0000053530.95952.FD
[12]	Danve A, O'Dell J. The Role of ¹⁸F Fluorodeoxyglucose Positron Emission Tomography Scanning in the Diagnosis and Management of Systemic Vasculitis[J]. Int J Rheum DisInt J Rheum Dis, 2015, 18(7): 714-724. doi: 10.1111/1756-185X.12713
[13]	李立伟, 金泉, 马璐娜, 等. 肝癌经动脉栓塞化疗后FDG PET显像的临床价值——附10例FDG PET和CT结果对照[J]. 中国医学影像技术中国医学影像技术, 2001, 17(11): 1074-1075. doi: 10.3321/j.issn:1003-3289.2001.11.020 Li LW, Jin Q, Ma LN, et al. Clinical Value of FDG PET Imaging in Monitoring Hepatocellular Carcinoma after Chemoembolization Compared FDG PET with CT in 10 Cases[J]. Chin Med Imag TechnolChin Med Imag Technol, 2001, 17(11): 1074-1075. doi: 10.3321/j.issn:1003-3289.2001.11.020
[14]	何玉林, 王雪梅, 包宝亮. ¹⁸F-FLT合成及其在PET/CT显像中的应用[J]. 内蒙古医学院学报内蒙古医学院学报, 2010, 32(2): 95-98. doi: 10.3969/j.issn.1004-2113.2010.02.005 He YL, Wang XM, Bao BL. THE SYNTHESIS AND APPLICATION OF ¹⁸F-FLT IN PET/CT IMAGING[J]. Acta Acad Med Nei MongolActa Acad Med Nei Mongol, 2010, 32(2): 95-98. doi: 10.3969/j.issn.1004-2113.2010.02.005
[15]	王甜甜, 赵晋华. ¹⁸F-FLT增殖显像机制及前期临床研究[J]. 国际放射医学核医学杂志国际放射医学核医学杂志, 2012, 36(1): 8-12. doi: 10.3760/cma.j.issn.1673-4114.2012.01.002 Wang TT, Zhao JH. The basis of ¹⁸F-3'-deoxy-3'-L-fluorothymidine as a proliferation tracer and preclinical study[J]. Int J Radiol Med Nucl MedInt J Radiol Med Nucl Med, 2012, 36(1): 8-12. doi: 10.3760/cma.j.issn.1673-4114.2012.01.002
[16]	陈晓婷, 赵鑫, 高振华, 等. 非小细胞肺癌¹⁸F-FLT PET显像结果与肿瘤细胞高增殖区的一致性探讨[J]. 山东医药山东医药, 2016, 56(6): 45-47. doi: 10.3969/j.issn.1002-266X.2016.06.016 Chen XT, Zhao X, Gao ZH, et al. Consistency between ¹⁸F-FLT PET imaging results and hyperproliferative regions of tumor cells[J]. Shandong MedShandong Med, 2016, 56(6): 45-47. doi: 10.3969/j.issn.1002-266X.2016.06.016
[17]	陈雷, 柳曦. ¹⁸F-FDG和¹⁸F-FLT的正电子发射断层显像对肿瘤放化疗疗效评价的实验研究[J]. 中国医药导报中国医药导报, 2013, 10(18): 41-43. doi: 10.3969/j.issn.1673-7210.2013.18.014 Chen L, Liu X. Experimental research of ¹⁸F-FDG and ¹⁸F-FLT PET in efficient evaluation of tumor chemotherapy[J]. Chin Med JChin Med J, 2013, 10(18): 41-43. doi: 10.3969/j.issn.1673-7210.2013.18.014
[18]	Buck AK, Halter G, Schirrmeister H, et al. Imaging Proliferation in Lung Tumors with PET: ¹⁸F-FLT Versus ¹⁸F-FDG[J]. J Nucl MedJ Nucl Med, 2003, 44(9): 1426-1431.
[19]	Troost EGC, Bussink J, Hoffmann AL, et al. ¹⁸F-FLT PET/CT for Early Response Monitoring and Dose Escalation in Oropharyngeal Tumors[J]. J Nucl MedJ Nucl Med, 2010, 51(6): 866-874. doi: 10.2967/jnumed.109.069310
[20]	Dittmann H, Dohmen BM, Paulsen F, et al. [¹⁸F]FLT PET for diagnosis and staging of thoracic tumours[J]. Eur J Nucl Med Mol ImagEur J Nucl Med Mol Imag, 2003, 30(10): 1407-1412. doi: 10.1007/s00259-003-1257-3
[21]	Timmer SAJ, Lubberink M, Germans T, et al. Potential of [¹¹C]acetate for measuring myocardial blood flow: Studies in normal subjects and patients with hypertrophic cardiomyopathy[J]. J Nucl CardiolJ Nucl Cardiol, 2010, 17(2): 264-275. doi: 10.1007/s12350-009-9181-y
[22]	Liu D, Khong PL, Gao YM, et al. Radiation Dosimetry of Whole-Body Dual-Tracer ¹⁸F-FDG and ¹¹C-Acetate PET/CT for Hepatocellular Carcinoma[J]. J Nucl Med Off Publ Soc Nucl MedJ Nucl Med Off Publ Soc Nucl Med, 2016, 57(6): 907-912. doi: 10.2967/jnumed.115.165944
[23]	霍力, 党永红, 崔瑞雪, 等. ¹¹C-乙酸盐PET双时相显像鉴别诊断肝原发肿瘤[J]. 中华核医学与分子影像杂志中华核医学与分子影像杂志, 2014, 34(2): 96-99. doi: 10.3760/cma.j.issn.2095-2848.2014.02.004 Huo L, Dang YH, Cui RX, et al. Detection of primary hepatoma with early and routine ¹¹C-acetate PET imaging[J]. Chin J Nucl Med Mol ImagChin J Nucl Med Mol Imag, 2014, 34(2): 96-99. doi: 10.3760/cma.j.issn.2095-2848.2014.02.004
[24]	孙爱君, 任茜, 刘健, 等. ¹¹C-乙酸盐PET和PET/CT在肿瘤显像中的应用[J]. 国际放射医学核医学杂志国际放射医学核医学杂志, 2013, 37(4): 243-247. doi: 10.3760/cma.j.issn.1673-4114.2013.04.013 Sun AJ, Ren X, Liu J, et al. The application of ¹¹C-acetate PET and PET-CT for tumors[J]. Int J Radiol Med Nucl MedInt J Radiol Med Nucl Med, 2013, 37(4): 243-247. doi: 10.3760/cma.j.issn.1673-4114.2013.04.013
[25]	Yoo SW, Kim DY, Lee C, et al. Small Bowel Metastasis From Hepatocellular Carcinoma Detected by ¹⁸F-FDG PET/CT But Not by ¹¹C-Acetate PET/CT[J]. Clin Nucl MedClin Nucl Med, 2017, 42(12): 966-967. doi: 10.1097/RLU.0000000000001882
[26]	Li SR, Peck-Radosavljevic M, Ubl P, et al. The value of [¹¹C]-acetate PET and[¹⁸F]-FDG PET in hepatocellular carcinoma before and after treatment with transarterial chemoembolization and bevacizumab[J]. Eur J Nucl Med Mol ImagEur J Nucl Med Mol Imag, 2017, 44(10): 1732-1741. doi: 10.1007/s00259-017-3724-2
[27]	Cheung TT, Ho CL, Lo CM, et al. ¹¹C-acetate and ¹⁸F-FDG PET/CT for clinical staging and selection of patients with hepatocellular carcinoma for liver transplantation on the basis of Milan criteria: surgeon's perspective[J]. J Nucl MedJ Nucl Med, 2013, 54(2): 192-200. doi: 10.2967/jnumed.112.107516
[28]	Mohsen B, Giorgio T, Rasoul ZS, et al. Application of ¹¹C-acetate positron-emission tomography (PET) imaging in prostate cancer: systematic review and meta-analysis of the literature[J]. BJU IntBJU Int, 2013, 112(8): 1062-1072. doi: 10.1111/bju.12279