[1] Matsui M, Corey DR.  Non-coding RNAs as drug targets[J]. Nat Rev Drug Dis, 2017, 16(3): 167-179.   doi: 10.1038/nrd.2016.117
[2] Ravasi T, Suzuki H, Pang KC, et al.  Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome[J]. Genome Res, 2006, 16(1): 11-19.   doi: 10.1101/gr.4200206
[3] Wang P, Li X, Gao Y, et al.  LnCeVar: a comprehensive database of genomic variations that disturb ceRNA network regulation[J]. Nucleic Acids Res, 2019, 48(D1): D111-D117.   doi: 10.1093/nar/gkz887
[4] 胡悦, 黄瑞雪.  肿瘤放射治疗抵抗相关lncRNA的研究进展[J]. 毒理学杂志, 2019, 30(4): 327-331.
Hu Y, Huang RX.  Advances in the study of lncRNA associated with tumor radiation therapy resistance[J]. J Toxicol, 2019, 30(4): 327-331.
[5] 于多, 吕欣, 金顺子.  长链非编码RNA的作用机制及其与肿瘤和放射敏感性的研究进展[J]. 中华放射医学与防护杂志, 2014, 34(8): 627-630.   doi: 10.3760/cma.j.issn.0254-5098.2014.08.017
Yu D, Lyu X, Jin SZ.  Advances in the mechanism of action of long-stranded non-coding RNAs and their association with tumor and radiosensitivity[J]. Chin J Radiol Med Prot, 2014, 34(8): 627-630.   doi: 10.3760/cma.j.issn.0254-5098.2014.08.017
[6]

Schmidbauer B, Menhart K, Hellwig D, et al. Differentiated thyroid cancer-treatment: state of the art[J/OL]. Int J Mol Sci, 2017, 18(6): 1292[2021-01-17]. https://www.mdpi.com/1422-0067/18/6/1292. DOI: 10.3390/ijms18061292.
[7] 周宇杰, 徐细明.  长链非编码RNA在放射治疗中的研究进展[J]. 临床误诊误治, 2017, 30(9): 106-110.   doi: 10.3969/j.issn.1002-3429.2017.09.037
Zhou YJ, Xu XM.  Advances in the study of long-stranded non-coding RNA in radiation therapy[J]. Clin Misdiag Misther, 2017, 30(9): 106-110.   doi: 10.3969/j.issn.1002-3429.2017.09.037
[8] Yang F, Deng XX, Ma WX, et al.  The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation[J]. Genome Biol, 2015, 16: 52-.   doi: 10.1186/s13059-015-0618-0
[9]

Hou Y, Zhang RX, Sun X. Enhancer lncRNAs influence chromatin interactions in different ways[J/OL]. Front Genet, 2019, 10: 936[2021-01-17]. https://www.frontiersin.org/articles/10.3389/fgene.2019.00936/full. DOI: 10.3389/fgene.2019.00936.
[10] Antonicka H, Sasarman F, Nishimura T, et al.  The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression[J]. Cell Metab, 2013, 17(3): 386-398.   doi: 10.1016/j.cmet.2013.02.006
[11] Chu C, Qu K, Zhong FL, et al.  Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions[J]. Mol Cell, 2011, 44(4): 667-678.   doi: 10.1016/j.molcel.2011.08.027
[12] Zhu JM, Chen SS, Yang BX, et al.  Molecular mechanisms of lncRNAs in regulating cancer cell radiosensitivity[J]. Biosci Rep, 2019, 39(8): BSR20190590-.   doi: 10.1042/BSR20190590
[13] Guo JH, Ding YH, Yang HB, et al.  RETRACTED: aberrant expression of lncRNA MALAT1 modulates radioresistance in colorectal cancer in vitro via miR-101-3p sponging[J]. Exp Mol Pathol, 2020, 115: 104448-.   doi: 10.1016/j.yexmp.2020.104448
[14] Liu RX, Zhang QT, Shen LP, et al.  Long noncoding RNA lnc-RI regulates DNA damage repair and radiation sensitivity of CRC cells through NHEJ pathway[J]. Cell Biol Toxicol, 2020, 36(5): 493-507.   doi: 10.1007/s10565-020-09524-6
[15] Zou YM, Yao S, Chen XQ, et al.  LncRNA OIP5-AS1 regulates radioresistance by targeting DYRK1A through miR-369-3p in colorectal cancer cells[J]. Eur J Cell Biol, 2018, 97(5): 369-378.   doi: 10.1016/j.ejcb.2018.04.005
[16] Yang PX, Yang Y, An WW, et al.  The long noncoding RNA-ROR promotes the resistance of radiotherapy for human colorectal cancer cells by targeting the p53/miR-145 pathway[J]. J Gastroenterol Hepatol, 2017, 32(4): 837-845.   doi: 10.1111/jgh.13606
[17] Zhang JN, Ding LX, Sun GF, et al.  Suppression of LINC00460 mediated the sensitization of HCT116 cells to ionizing radiation by inhibiting epithelial-mesenchymal transition[J]. Toxicol Res (Camb), 2020, 9(2): 107-116.   doi: 10.1093/toxres/tfaa010
[18] Chen WZ, Zhang YS, Wang HJ, et al.  LINC00473/miR-374a-5p regulates esophageal squamous cell carcinoma via targeting SPIN1 to weaken the effect of radiotherapy[J]. J Cell Biochem, 2019, 120(9): 14562-14572.   doi: 10.1002/jcb.28717
[19]

Yao Q, Yang J, Liu T, et al. Long noncoding RNA MALAT1 promotes the stemness of esophageal squamous cell carcinoma by enhancing YAP transcriptional activity[J/OL]. FEBS Open Bio, 2019, 9(8): 1392−1402[2021-01-17]. https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.12676. DOI: 10.1002/2211-5463.12676.
[20]

Chen MQ, Liu PP, Chen YG, et al. Long noncoding RNA FAM201A mediates the radiosensitivity of esophageal squamous cell cancer by regulating ATM and mTOR expression via miR-101[J/OL]. Front Genet, 2018, 9: 611[2021-01-17]. https://www.frontiersin.org/articles/10.3389/fgene.2018.00611/full. DOI: 10.3389/fgene.2018.00611.
[21] Li ZY, Li HF, Zhang YY, et al.  Value of long non-coding RNA Rpph1 in esophageal cancer and its effect on cancer cell sensitivity to radiotherapy[J]. World J Gastroenterol, 2020, 26(15): 1775-1791.   doi: 10.3748/wjg.v26.i15.1775
[22] Wang P, Yang ZB, Ye T, et al.  LncTUG1/miR-144-3p affect the radiosensitivity of esophageal squamous cell carcinoma by competitively regulating c-MET[J]. J Exp Clin Cancer Res, 2020, 39(1): 7-.   doi: 10.1186/s13046-019-1519-y
[23] Chen X, Zhang NB.  Downregulation of lncRNA NEAT1_2 radiosensitizes hepatocellular carcinoma cells through regulation of miR-101-3p/WEE1 axis[J]. Cell Biol Int, 2019, 43(1): 44-55.   doi: 10.1002/cbin.11077
[24] Song W, Zhang JJ, Xia QX, et al.  Down-regulated lncRNA TP73-AS1 reduces radioresistance in hepatocellular carcinoma via the PTEN/Akt signaling pathway[J]. Cell Cycle, 2019, 18(22): 3177-3188.   doi: 10.1080/15384101.2019.1671089
[25]

Huang MD, Chen WM, Qi FZ, et al. Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2[J/OL]. Mol Cancer, 2015, 14: 165[2021-01-17]. https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-015-0431-0. DOI: 10.1186/s12943-015-0431-0.
[26] 孟碧, 王梦洁, 刘阳晨.  LncRNA在消化道肿瘤放疗敏感性中的作用及机制[J]. 癌症进展, 2017, 15(7): 740-744.   doi: 10.11877/j.issn.1672-1535.2017.15.07.06
Meng B, Wang MJ, Liu YC.  The role and mechanism of lncRNA in the sensitivity of radiotherapy for gastrointestinal tumors[J]. Oncol Prog, 2017, 15(7): 740-744.   doi: 10.11877/j.issn.1672-1535.2017.15.07.06
[27] Zhou Y, He P, Xie XH, et al.  Knockdown of SUMO1P3 represses tumor growth and invasion and enhances radiosensitivity in hepatocellular carcinoma[J]. Mol Cell Biochem, 2019, 450(1/2): 125-134.   doi: 10.1007/s11010-018-3379-8
[28] Hu XG, Ding D, Zhang JY, et al.  Knockdown of lncRNA HOTAIR sensitizes breast cancer cells to ionizing radiation through activating miR-218[J]. Biosci Rep, 2019, 39(4): BSR20181038-.   doi: 10.1042/BSR20181038
[29] Zhang SQ, Wang B, Xiao HW, et al.  LncRNA HOTAIR enhances breast cancer radioresistance through facilitating HSPA1A expression via sequestering miR-449b-5p[J]. Thorac Cancer, 2020, 11(7): 1801-1816.   doi: 10.1111/1759-7714.13450
[30]

Zhang N, Zeng X, Sun CN, et al. LncRNA LINC00963 promotes tumorigenesis and radioresistance in breast cancer by sponging miR-324-3p and inducing ACK1 expression[J/OL]. Mol Ther Nucleic Acids, 2019, 18: 871−881[2021-01-17]. https://linkinghub.elsevier.com/retrieve/pii/S2162253119303233. DOI: 10.1016/j.omtn.2019.09.033.
[31]

Wang BY, Zheng JL, Li R, et al. Long noncoding RNA LINC02582 acts downstream of miR-200c to promote radioresistance through CHK1 in breast cancer cells[J/OL]. Cell Death Dis, 2019, 10(10): 764[2021-01-17]. https://www.nature.com/articles/s41419-019-1996-0. DOI: 10.1038/s41419-019-1996-0.
[32] Liu L, Zhu Y, Liu AM, et al.  Long noncoding RNA LINC00511 involves in breast cancer recurrence and radioresistance by regulating STXBP4 expression via miR-185[J]. Eur Rev Med Pharmacol Sci, 2019, 23(17): 7457-7468.   doi: 10.26355/eurrev_201909_18855
[33]

Shi R, Wu P, Liu M, et al. Knockdown of lncRNA PCAT6 enhances radiosensitivity in triple-negative breast cancer cells by regulating miR-185-5p/TPD52 axis[J/OL]. Onco Targets Ther, 2020, 13: 3025−3037[2021-01-17]. https://www.dovepress.com/knockdown-of-lncrna-pcat6-enhances-radiosensitivity-in-triple-negative-peer-reviewed-fulltext-article-OTT. DOI: 10.2147/OTT.S237559.
[34]

Han YY, Liu K, Xie J, et al. LINC00114 promoted nasopharyngeal carcinoma progression and radioresistance in vitro and in vivo through regulating ERK/JNK signaling pathway via targeting miR-203[J/OL]. Eur Rev Med Pharmacol Sci, 2020, 24(5): 2491−2504[2021-01-17]. https://www.europeanreview.org/article/20517. DOI: 10.26355/eurrev_202003_20517.
[35] Jin C, Yan BC, Lu Q, et al.  The role of MALAT1/miR-1/slug axis on radioresistance in nasopharyngeal carcinoma[J]. Tumour Biol, 2016, 37(3): 4025-4033.   doi: 10.1007/s13277-015-4227-z
[36] Qian W, Ren ZT, Lu XG.  Knockdown of long non-coding RNA TUG1 suppresses nasopharyngeal carcinoma progression by inhibiting epithelial-mesenchymal transition (EMT) via the promotion of miR-384[J]. Biochem Biophys Res Commun, 2019, 509(1): 56-63.   doi: 10.1016/j.bbrc.2018.12.011
[37]

Xiao YW, Pan JJ, Geng Q, et al. LncRNA MALAT1 increases the stemness of gastric cancer cells via enhancing SOX2 mRNA stability[J/OL]. FEBS Open Bio, 2019, 9(7): 1212−1222[2021-01-17]. https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.12649. DOI: 10.1002/2211-5463.12649.
[38]

Xiao J, Lin LL, Luo DK, et al. Long noncoding RNA TRPM2-AS acts as a microRNA sponge of miR-612 to promote gastric cancer progression and radioresistance[J/OL]. Oncogenesis, 2020, 9(3): 29[2021-01-17]. https://www.nature.com/articles/s41389-020-0215-2. DOI: 10.1038/s41389-020-0215-2.
[39] Chen LJ, Yuan DF, Yang YC, et al.  LincRNA-p21 enhances the sensitivity of radiotherapy for gastric cancer by targeting the β-catenin signaling pathway[J]. J Cell Biochem, 2019, 120(4): 6178-6187.   doi: 10.1002/jcb.27905
[40]

Wang D, Hu Y. Long non-coding RNA PVT1 competitively binds microRNA-424-5p to regulate CARM1 in radiosensitivity of non-small-cell lung cancer[J/OL]. Mol Ther Nucleic Acids, 2019, 16: 130−140[2021-01-17]. https://linkinghub.elsevier.com/retrieve/pii/S2162253118303214. DOI: 10.1016/j.omtn.2018.12.006.
[41] Yu ZW, Wang GB, Zhang CL, et al.  LncRNA SBF2-AS1 affects the radiosensitivity of non-small cell lung cancer via modulating microRNA-302a/MBNL3 axis[J]. Cell Cycle, 2020, 19(3): 300-316.   doi: 10.1080/15384101.2019.1708016
[42] Liu AM, Zhu Y, Huang ZW, et al.  Long noncoding RNA FAM201A involves in radioresistance of non-small-cell lung cancer by enhancing EGFR expression via miR-370[J]. Eur Rev Med Pharmacol Sci, 2019, 23(13): 5802-5814.   doi: 10.26355/eurrev_201907_18319
[43] Chen L, Ren P, Zhang YD, et al.  Long non-coding RNA GAS5 increases the radiosensitivity of A549 cells through interaction with the miR-21/PTEN/Akt axis[J]. Oncol Rep, 2020, 43(3): 897-907.   doi: 10.3892/or.2020.7467
[44] Hou JQ, Wang YJ, Zhang HM, et al.  Silencing of LINC00461 enhances radiosensitivity of lung adenocarcinoma cells by down-regulating HOXA10 via microRNA-195[J]. J Cell Mol Med, 2020, 24(5): 2879-2890.   doi: 10.1111/jcmm.14859
[45] Zhang M, Gao C, Yang Y, et al.  Long noncoding RNA CRNDE/PRC2 participated in the radiotherapy resistance of human lung adenocarcinoma through targeting p21 expression[J]. Oncol Res, 2018, 26(8): 1245-1255.   doi: 10.3727/096504017X14944585873668
[46] Lu HZ, He Y, Lin L, et al.  Long non-coding RNA MALAT1 modulates radiosensitivity of HR-HPV+ cervical cancer via sponging miR-145[J]. Tumor Biol, 2016, 37(2): 1683-1691.   doi: 10.1007/s13277-015-3946-5
[47] Zhao H, Zheng GH, Li GC, et al.  Long noncoding RNA LINC00958 regulates cell sensitivity to radiotherapy through RRM2 by binding to microRNA-5095 in cervical cancer[J]. J Cell Physiol, 2019, 234(12): 23349-23359.   doi: 10.1002/jcp.28902
[48] Gao JB, Liu LY, Li GL, et al.  LncRNA GAS5 confers the radio sensitivity of cervical cancer cells via regulating miR-106b/IER3 axis[J]. Int J Biol Macromol, 2019, 126: 994-1001.   doi: 10.1016/j.ijbiomac.2018.12.176
[49]

Li N, Meng DD, Gao L, et al. Overexpression of HOTAIR leads to radioresistance of human cervical cancer via promoting HIF-1α expression[J/OL]. Radiat Oncol, 2018, 13(1): 210[2021-01-17]. https://ro-journal.biomedcentral.com/articles/10.1186/s13014-018-1153-4. DOI: 10.1186/s13014-018-1153-4.
[50]

Yang Z, Gu QY, Wang Y, et al. Heavy-ion carbon radiation regulates long non-coding RNAs in cervical cancer HeLa cells[J/OL]. J Cancer, 2019, 10(21): 5022-5030[2021-01-17]. https://www.jcancer.org/v10p5022.htm. DOI: 10.7150/jca.30846.
[51]

Fang YZ, Zhang L, Li ZH, et al. MicroRNAs in DNA damage response, carcinogenesis, and chemoresistance[J/OL]. Int Rev Cell Mol Biol, 2017, 333: 1−49[2021-01-17]. https://www.sciencedirect.com/science/article/abs/pii/S1937644817300266. DOI: 10.1016/bs.ircmb.2017.03.001.