[1] Siegel RL, Miller KD, Jemal A.  Cancer statistics, 2018[J]. CA Cancer J Clin, 2018, 68(1): 7-30.   doi: 10.3322/caac.21442
[2] 中国抗癌协会乳腺癌专业委员会.  中国抗癌协会乳腺癌诊治指南与规范(2017年版)[J]. 中国癌症杂志, 2017, 27(9): 695-759.   doi: 10.19401/j.cnki.1007-3639.2017.09.004
China Cancer Association Breast Cancer Professional Committee.  Guidelines and Guidelines for the Diagnosis and Treatment of Breast Cancer by the China Anti-Cancer Association(2017)[J]. China Oncol, 2017, 27(9): 695-759.   doi: 10.19401/j.cnki.1007-3639.2017.09.004
[3] Butson MJ, Cheung T, Yu P, et al.  Effects on skin dose from unwanted air gaps under bolus in photon beam radiotherapy[J]. Radiat Meas, 2000, 32(3): 201-204.   doi: 10.1016/s1350-4487(99)00276-0
[4] Kong M, Holloway L.  An investigation of central axis depth dose distribution perturbation due to an air gap between patient and bolus for electron beams[J]. Australas Phys Eng Sci Med, 2007, 30(2): 111-119.   doi: 10.1007/bf03178415
[5] Khan Y, Villarreal-Barajas JE, Udowicz M, et al.  Clinical and Dosimetric Implications of Air Gaps Between Bolus and Skin Surface During Radiation Therapy[J]. J Cancer Ther, 2013, 4(7): 1251-1255.   doi: 10.4236/jct.2013.47147
[6] Sharma SC, Johnson MW.  Surface dose perturbation due to air gap between patient and bolus for electron beams[J]. Med Phys, 1993, 20(2): 377-378.   doi: 10.1118/1.597079
[7] Vyas V, Palmer L, Mudge R, et al.  On bolus for megavoltage photon and electron radiation therapy[J]. Med Dosim, 2013, 38(3): 268-273.   doi: 10.1016/j.meddos.2013.02.007
[8]

Su SQ, Moran K, Robar JL. Design and production of 3D printed bolus for electron radiation therapy[J/OL]. J Appl Clin Med Phys, 2014, 15(4): 194−211[2019-02-22]. https://aapm.onlinelibrary.wiley.com/doi/full/10.1120/jacmp.v15i4.4831. DOI: 10.1120/jacmp.v15i4.4831.

[9] 王峻峰, 李定宇, 黄章玲, 等.  Merkel细胞癌电子线放疗中3D打印补偿物的模拟应用[J]. 中华放射肿瘤学杂志, 2016, 25(9): 999-1002.   doi: 10.3760/cma.j.issn.1004-4221.2016.09.022
Wang JF, Li DY, Huang ZL, et al.  Simulation and application of 3D printed compensator in electron radiation therapy for Merkel cell carcinoma[J]. Chin J Radiat Oncol, 2016, 25(9): 999-1002.   doi: 10.3760/cma.j.issn.1004-4221.2016.09.022
[10] Park JW, Yea JW.  Three-dimensional customized bolus for intensity-modulated radiotherapy in a patient with Kimura's disease involving the auricle[J]. Cancer Radiother, 2016, 20(3): 205-209.   doi: 10.1016/j.canrad.2015.11.003
[11] Canters RA, Lips IM, Wendling M, et al.  Clinical implementation of 3D printing in the construction of patient specific bolus for electron beam radiotherapy for non-melanoma skin cancer[J]. Radiother Oncol, 2016, 121(1): 148-153.   doi: 10.1016/j.radonc.2016.07.011
[12] 张敏, 赵波, 尹金鹏, 等.  新型3D打印组织补偿物的放疗应用研究[J]. 中华放射肿瘤学杂志, 2017, 26(2): 210-214.   doi: 10.3760/cma.j.issn.1004-4221.2017.02.018
Zhang M, Zhao B, Yin JP, et al.  Application of new three-dimensional printed tissue compensators in radiotherapy[J]. Chin J Radiat Oncol, 2017, 26(2): 210-214.   doi: 10.3760/cma.j.issn.1004-4221.2017.02.018
[13]

Park SY, Choi CH, Park JM, et al. A Patient-Specific Polylactic Acid Bolus Made by A 3D Printer for Breast Cancer Radiation Therapy[J/OL]. PLoS One, 2016, 11(12): e0168063[2019-02-22]. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168063. DOI: 10.1371/journal.pone.0168063.

[14] 侯彦杰, 于江平, 王永强, 等.  3D打印胸壁硅胶bolus制作及临床前研究[J]. 中华放射肿瘤学杂志, 2018, 27(9): 835-838.   doi: 10.3760/cma.j.issn.1004-4221.2018.09.010
Hou YJ, Yu JP, Wang YQ, et al.  Fabrication and pre-clinical application of patient-specific 3D silicone rubber bolus for chest wall[J]. Chin J Radiat Oncol, 2018, 27(9): 835-838.   doi: 10.3760/cma.j.issn.1004-4221.2018.09.010
[15] Lindegaard JC, Madsen ML, Traberg A, et al.  Individualised 3D printed vaginal template for MRI guided brachytherapy in locally advanced cervical cancer[J]. Radiother Oncol, 2016, 118(1): 173-175.   doi: 10.1016/j.radonc.2015.12.012
[16] Sethi R, Cunha A, Mellis K, et al.  Clinical applications of custom-made vaginal cylinders constructed using three-dimensional printing technology[J]. J Contemp Brachytherapy, 2016, 8(3): 208-214.   doi: 10.5114/jcb.2016.60679
[17] 于浪, 连欣, 晏俊芳, 等.  3D打印技术在CT引导宫颈癌术后阴道残端肿瘤近距离治疗中应用[J]. 中华放射肿瘤学杂志, 2016, 25(9): 965-967.   doi: 10.3760/cma.j.issn.1004-4221.2016.09.013
Yu L, Lian X, Yan JF, et al.  Application of 3D printing technology in brachytherapy for vaginal stump tumor after CT-guided cervical carcinoma surgery[J]. Chin J Radiat Oncol, 2016, 25(9): 965-967.   doi: 10.3760/cma.j.issn.1004-4221.2016.09.013
[18] 王云龙, 李昕迪, 赵钰哲.  3D打印技术在阴道癌放射治疗中的应用研究[J]. 中国数字医学, 2018, 13(6): 64-65, 71.   doi: 10.3969/j.issn.1673-7571.2018.06.022
Wang YL, Li XD, Zhao YZ.  Study on the Application of 3D Printing Technology in the Treatment of Vaginal Cancer[J]. China Digit Med, 2018, 13(6): 64-65, 71.   doi: 10.3969/j.issn.1673-7571.2018.06.022
[19] Kaanders JHAM, Fleming TJ, Ang KK, et al.  Devices valuable in head and neck radiotherapy[J]. Int J Radiat Oncol Biol Phys, 1992, 23(3): 639-645.   doi: 10.1016/0360-3016(92)90023-B
[20] Nayar S, Brett R, Clayton N, et al.  The effect of a radiation positioning stent (RPS) in the reduction of radiation dosage to the opposing jaw and maintenance of mouth opening after radiation therapy[J]. Eur J Prosthodont Restor Dent, 2016, 24(2): 71-77.
[21]

涂文勇, 丁继平, 胡海生, 等. 口腔放疗用上下分隔型支架及其制作方法: 中国, CN104043205A[P]. 2014-09-17.

Tu WY, Ding JP, Hu HS, et al. Stent with upper and lower separation for oral radiotherapy and its manufacturing method: CN, CN104043205A[P]. 2014-09-17.

[22] 丁继平, 涂文勇, 胡海生, 等.  3D打印口腔支架对舌癌术后调强放疗危及器官的剂量学影响[J]. 中华肿瘤防治杂志, 2015, 22(15): 1221-1225.
Ding JP, Tu WY, Hu HS, et al.  Influence on normal tissue dosimetry in intensity-modulated radiotherapy of post-operative lingual carcinoma patients with 3D intraoral stent[J]. Chin J Cancer Prev Treat, 2015, 22(15): 1221-1225.
[23] 丁继平, 涂文勇, 胡海生, 等.  基于3D打印技术的个体化口腔放疗支架的设计[J]. 中国医疗器械杂志, 2017, 41(6): 458-459, 468.   doi: 10.3969/j.issn.1671-7104.2017.06.018
Ding JP, Tu WY, Hu HS, et al.  Design of Individualized Oral Radiotherapy Stent Based on 3D Printing Technique[J]. Chin J Med Instrument, 2017, 41(6): 458-459, 468.   doi: 10.3969/j.issn.1671-7104.2017.06.018
[24]

Wilke CT, Zaid M, Chung C, et al. Design and fabrication of a 3D-printed oral stent for head and neck radiotherapy from routine diagnostic imaging[J/OL]. 3D Print Med, 2017, 3(1): 12 [2019-02-22]. https://threedmedprint.biomedcentral.com/articles/10.1186/s41205-017-0021-4. DOI: 10.1186/s41205-017-0021-4.

[25] Zhao YZ, Moran K, Yewondwossen M, et al.  Clinical applications of 3-dimensional printing in radiation therapy[J]. Med Dosim, 2017, 42(2): 150-155.   doi: 10.1016/j.meddos.2017.03.001
[26] 赵家成, 李多杰, 段诗苗, 等.  头颈肩面罩在鼻咽癌调强放疗中的固定效果与精度比较[J]. 中华全科医学, 2012, 10(3): 363, 412-.
Zhao JC, Li DJ, Duan SM, et al.  The Fix Effects and Accuracy of the Head, Neck and Shoulder Mask in Intensity-modulated Radiotherapy of Nasopharyngeal Carcinoma[J]. Chin J Gen Pract, 2012, 10(3): 363, 412-.
[27] 吴少雄, 温志祥, 何晓华, 等.  一种新型三维头颈放疗固定装置的研制及临床验证[J]. 癌症, 2002, 21(11): 1265-1266.   doi: 10.3321/j.issn:1000-467X.2002.11.024
Wu SX, Wen ZX, He XH, et al.  Development and clinical verification of a new type of three-dimensional head and neck radiotherapy fixation device[J]. Chin J Cancer, 2002, 21(11): 1265-1266.   doi: 10.3321/j.issn:1000-467X.2002.11.024
[28] Sato K, Takeda K, Dobashi S, et al.  Evaluation of the Positional Accuracy and Dosimetric Properties of a Three-dimensional Printed Device for Head and Neck Immobilization[J]. Jpn J Radiol Technol, 2017, 73(1): 57-65.   doi: 10.6009/jjrt.2017_JSRT_73.1.57
[29]

Haefner MF, Giesel FL, Mattke M, et al. 3D-Printed masks as a new approach for immobilization in radiotherapy—a study of positioning accuracy[J/OL]. Oncotarget, 2018, 9(5): 6490−6498 [2019-02-22]. http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=24032&path[]=75562. DOI: 10.18632/oncotarget.24032.

[30] 吉喆, 姜玉良, 郭福新, 等.  3D打印模板联合CT引导下放射性粒子植入治疗椎旁/腹膜后恶性肿瘤的剂量学验证观察[J]. 中华医学杂志, 2017, 97(13): 996-1000.   doi: 10.3760/cma.j.issn.0376-2491.2017.13.007
Ji Z, Jiang YL, Guo FX, et al.  Dosimetry verification of radioactive seed implantation with 3D printing template and CT guidance for paravertebral/retroperitoneal malignant tumor[J]. Nat Med J China, 2017, 97(13): 996-1000.   doi: 10.3760/cma.j.issn.0376-2491.2017.13.007
[31] 王皓, 王俊杰, 姜玉良, 等.  3D打印模板联合CT引导125I粒子治疗盆腔复发直肠癌的剂量学分析[J]. 中华医学杂志, 2016, 96(47): 3782-3786.   doi: 10.3760/cma.j.issn.0376-2491.2016.47.003
Wang H, Wang JJ, Jiang YL, et al.  CT guidance 125I seed implantation for pelvic recurrent rectal cancer assisted by 3D printing individual non-coplanar template[J]. Nat Med J China, 2016, 96(47): 3782-3786.   doi: 10.3760/cma.j.issn.0376-2491.2016.47.003
[32] 姜玉良, 王皓, 吉喆, 等.  CT引导辅助3D打印个体化非共面模板指导125I粒子治疗盆腔复发肿瘤剂量学研究[J]. 中华放射肿瘤学杂志, 2016, 25(9): 959-964.   doi: 10.3760/cma.j.issn.1004-4221.2016.09.012
Jiang YL, Wang H, Ji Z, et al.  Computed tomography image-guided and personalized 3D printed template-assisted 125-iodine seed implantation for recurrent pelvic tumor: a dosimetric study[J]. Chin J Radiat Oncol, 2016, 25(9): 959-964.   doi: 10.3760/cma.j.issn.1004-4221.2016.09.012
[33] 孙海涛, 姚丽红, 王俊杰, 等.  3D打印非共面模板引导125I粒子组织间近距离治疗盆腔肿瘤个体化设计[J]. 中华放射医学与防护杂志, 2017, 37(7): 485-489.   doi: 10.3760/cma.j.issn.0254-5098.2017.07.002
Sun HT, Yao LH, Wang JJ, et al.  3D-printing non-coplanar template assisted 125I seed implantation for pelvic tumor: individual template design method[J]. Chin J Radiol Med Prot, 2017, 37(7): 485-489.   doi: 10.3760/cma.j.issn.0254-5098.2017.07.002
[34] 郭福新, 姜玉良, 吉喆, 等.  3D打印非共面模板辅助CT引导125Ⅰ粒子植入治疗锁骨上复发转移癌的剂量学研究[J]. 北京大学学报: 医学版, 2017, 49(3): 506-511.   doi: 10.3969/j.issn.1671-167X.2017.03.022
Guo FX, Jiang YL, Ji Z, et al.  3D printed template-assisted and computed tomography image-guided 125-iodine seed implantation for supraclavicular metastatic tumor: a dosimetric study[J]. J Peking Univ: Health Sci, 2017, 49(3): 506-511.   doi: 10.3969/j.issn.1671-167X.2017.03.022
[35] 姜玉良, 吉喆, 郭福新, 等.  CT引导3D打印非共面模板辅助125I粒子治疗头颈部复发转移癌不良反应研究[J]. 中华放射医学与防护杂志, 2017, 37(7): 495-499.   doi: 10.3760/cma.j.issn.0254-5098.2017.07.004
Jiang YL, Ji Z, Guo FX, et al.  Side effect of radioactive 125I seed implantation for recurrent malignant tumor of head and neck assisted by 3D-printing individual guide plate[J]. Chin J Radiol Med Prot, 2017, 37(7): 495-499.   doi: 10.3760/cma.j.issn.0254-5098.2017.07.004
[36] 吉喆, 姜玉良, 郭福新, 等.  3D打印非共面模板辅助CT引导放射性粒子植入治疗胸部恶性肿瘤剂量学评估[J]. 中华放射肿瘤学杂志, 2017, 26(7): 754-758.   doi: 10.3760/cma.j.issn.1004-4221.2017.07.007
Ji Z, Jiang YL, Guo FX, et al.  Dosimetric assessment of CT-guided radioactive seed implantation assisted by 3D printing non-coplanar template in treatment of chest malignant tumor[J]. Chin J Radiat Oncol, 2017, 26(7): 754-758.   doi: 10.3760/cma.j.issn.1004-4221.2017.07.007
[37] Wang JJ, Zhang FJ, Guo JH, et al.  Expert consensus workshop report: Guideline for three-dimensional printing template-assisted computed tomography-guided 125I seeds interstitial implantation brachytherapy[J]. J Cancer Res Ther, 2017, 13(4): 607-612.   doi: 10.4103/jcrt.JCRT_412_17
[38] 王俊杰, 柴树德, 郑广钧, 等.  3D打印模板辅助CT引导放射性125I粒子植入治疗肿瘤专家共识[J]. 中华放射医学与防护杂志, 2017, 37(3): 161-170.   doi: 10.3760/cma.j.issn.0254-5098.2017.03.001
Wang JJ, Chai SD, Zheng GJ, et al.  Expert consensus on 3D-printing template assisted CT-guided radioactive 125I seed implantation brachytherapy[J]. Chin J Radiol Med Prot, 2017, 37(3): 161-170.   doi: 10.3760/cma.j.issn.0254-5098.2017.03.001
[39] Huang MW, Zhang JG, Zheng L, et al.  Accuracy evaluation of a 3D-printed individual template for needle guidance in head and neck brachytherapy[J]. J Radiat Res, 2016, 57(6): 662-667.   doi: 10.1093/jrr/rrw033
[40] Ji Z, Jiang YL, Guo FX, et al.  Dosimetry verification of radioactive seed implantation for malignant tumors assisted by 3D printing individual templates and CT guidance[J]. Appl Radiat Isot, 2017, 124: 68-74.   doi: 10.1016/j.apradiso.2016.12.009
[41]

Han T, Yang XD, Xu Y, et al. Therapeutic value of 3-D printing template-assisted 125I-seed implantation in the treatment of malignant liver tumors[J/OL]. Onco Targets Ther, 2017, 10: 3277−3283[2019-02-22]. https://www.dovepress.com/therapeutic-value-of-3-d-printing-template-assisted-125i-seed-implanta-peer-reviewed-article-OTT. DOI: 10.2147/OTT.S134290.

[42]

Jiang YL, Ji Z, Guo FX, et al. Side effects of CT-guided implantation of 125I seeds for recurrent malignant tumors of the head and neck assisted by 3D printing non co-planar template[J/OL]. Radiat Oncol, 2018, 13(1): 18[2019-02-22]. https://ro-journal.biomedcentral.com/articles/10.1186/s13014-018-0959-4. DOI: 10.1186/s13014-018-0959-4.