[1] Siegel RL, Miller KD, Fuchs HE, et al.  Cancer statistics, 2022[J]. CA Cancer J Clin, 2022, 72(1): 7-33.   doi: 10.3322/caac.21708
[2]

Du LB, Zhao ZX, Zheng RS, et al. Epidemiology of thyroid cancer: incidence and mortality in China, 2015[J/OL]. Front Oncol, 2020, 10: 1702[2022-04-24]. https://www.frontiersin.org/articles/10.3389/fonc.2020.01702/full. DOI: 10.3389/fonc.2020.01702.

[3] Fraser S, Zaidi N, Norlén O, et al.  Incidence and risk factors for occult level 3 lymph node metastases in papillary thyroid cancer[J]. Ann Surg Oncol, 2016, 23(11): 3587-3592.   doi: 10.1245/s10434-016-5254-8
[4] 张浩.  分化型甲状腺癌术后复发的处理策略[J]. 中华普外科手术学杂志: 电子版, 2016, 10(5): 373-375.   doi: 10.3877/cma.j.issn.1674-3946.2016.05.004
Zhang H.  Management of recurrent nodal disease in patients with differentiated thyroid cancer[J]. Chin J Oper Proc Gen Surg (Electron Ed), 2016, 10(5): 373-375.   doi: 10.3877/cma.j.issn.1674-3946.2016.05.004
[5] Duong T, Koopman P, Francois M.  Tumor lymphangiogenesis as a potential therapeutic target[J]. J Oncol, 2012, 2012: 204946-.   doi: 10.1155/2012/204946
[6] Stacker SA, Williams SP, Karnezis T, et al.  Lymphangiogenesis and lymphatic vessel remodelling in cancer[J]. Nat Rev Cancer, 2014, 14(3): 159-172.   doi: 10.1038/nrc3677
[7]

Gogineni A, Caunt M, Crow A, et al. Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis[J/OL]. PLoS One, 2013, 8(7): e68755[2022-04-24]. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068755. DOI: 10.1371/journal.pone.0068755.

[8] Jeltsch M, Kaipainen A, Joukov V, et al.  Hyperplasia of lymphatic vessels in VEGF-C transgenic mice[J]. Science, 1997, 276(5317): 1423-1425.   doi: 10.1126/science.276.5317.1423
[9] Alitalo A, Detmar M.  Interaction of tumor cells and lymphatic vessels in cancer progression[J]. Oncogene, 2012, 31(42): 4499-4508.   doi: 10.1038/onc.2011.602
[10] Alitalo K, Carmeliet P.  Molecular mechanisms of lymphangiogenesis in health and disease[J]. Cancer Cell, 2002, 1(3): 219-227.   doi: 10.1016/s1535-6108(02)00051-x
[11] Jang JY, Kim DS, Park HY, et al.  Preoperative serum VEGF-C but not VEGF-A level is correlated with lateral neck metastasis in papillary thyroid carcinoma[J]. Head Neck, 2019, 41(8): 2602-2609.   doi: 10.1002/hed.25729
[12] Yasuoka H, Nakamura Y, Zuo H, et al.  VEGF-D expression and lymph vessels play an important role for lymph node metastasis in papillary thyroid carcinoma[J]. Mod Pathol, 2005, 18(8): 1127-1133.   doi: 10.1038/modpathol.3800402
[13] Bumber B, Marjanovic Kavanagh M, Jakovcevic A, et al.  Role of matrix metalloproteinases and their inhibitors in the development of cervical metastases in papillary thyroid cancer[J]. Clin Otolaryngol, 2020, 45(1): 55-62.   doi: 10.1111/coa.13466
[14] 中华人民共和国国家卫生健康委员会.  甲状腺癌诊疗规范(2018年版)[J]. 中华普通外科学文献: 电子版, 2019, 13(1): 1-15.   doi: 10.3877/cma.j.issn.1674-0793.2019.01.001
National Health Commission of the People's Republic of China.  Diagnosis and treatment guidelines for thyroid cancer (2018 edition)[J]. Chin Arch Gen Surg (Electron Ed), 2019, 13(1): 1-15.   doi: 10.3877/cma.j.issn.1674-0793.2019.01.001
[15]

Attard A, Paladino NC, Lo Monte AI, et al. Skip metastases to lateral cervical lymph nodes in differentiated thyroid cancer: a systematic review[J/OL]. BMC Surg, 2019, 18(S1): S112[2022-04-24]. https://bmcsurg.biomedcentral.com/articles/10.1186/s12893-018-0435-y. DOI: 10.1186/s12893-018-0435-y.

[16]

Liu CX, Xiao C, Chen JJ, et al. Risk factor analysis for predicting cervical lymph node metastasis in papillary thyroid carcinoma: a study of 966 patients[J/OL]. BMC Cancer, 2019, 19(1): 622[2022-04-24]. https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5835-6. DOI: 10.1186/s12885-019-5835-6.

[17] Sakorafas GH, Koureas A, Mpampali I, et al.  Patterns of lymph node metastasis in differentiated thyroid cancer; clinical implications with particular emphasis on the emerging role of compartment-oriented lymph node dissection[J]. Oncol Res Treat, 2019, 42(3): 143-147.   doi: 10.1159/000488905
[18] Zhao HQ, Huang T, Li HH.  Risk factors for skip metastasis and lateral lymph node metastasis of papillary thyroid cancer[J]. Surgery, 2019, 166(1): 55-60.   doi: 10.1016/j.surg.2019.01.025
[19] Lin P, Yao ZN, Sun Y, et al.  Deciphering novel biomarkers of lymph node metastasis of thyroid papillary microcarcinoma using proteomic analysis of ultrasound-guided fine-needle aspiration biopsy samples[J]. J Proteomics, 2019, 204: 103414-.   doi: 10.1016/j.jprot.2019.103414
[20] Zhan SH, Wang TX, Wang M, et al.  In-depth proteomics analysis to identify biomarkers of papillary thyroid cancer patients older than 45 years with different degrees of lymph node metastases[J]. Proteomics Clin Appl, 2019, 13(5): e1900030-.   doi: 10.1002/prca.201900030
[21] Xing ZC, Qiu YX, Yang QR, et al.  Thyroid cancer neck lymph nodes metastasis: meta-analysis of US and CT diagnosis[J]. Eur J Radiol, 2020, 129: 109103-.   doi: 10.1016/j.ejrad.2020.109103
[22] Tian XQ, Song Q, Xie F, et al.  Papillary thyroid carcinoma: an ultrasound-based nomogram improves the prediction of lymph node metastases in the central compartment[J]. Eur Radiol, 2020, 30(11): 5881-5893.   doi: 10.1007/s00330-020-06906-6
[23] Hwang HS, Orloff LA.  Efficacy of preoperative neck ultrasound in the detection of cervical lymph node metastasis from thyroid cancer[J]. Laryngoscope, 2011, 121(3): 487-491.   doi: 10.1002/lary.21227
[24] Xu YX, Wu DP, Wu WT, et al.  Diagnostic value of cytology, thyroglobulin, and combination of them in fine-needle aspiration of metastatic lymph nodes in patients with differentiated thyroid cancer: a systematic review and network meta-analysis[J]. Medicine (Baltimore), 2019, 98(45): e17859-.   doi: 10.1097/MD.0000000000017859
[25] Suh CH, Baek JH, Choi YJ, et al.  Performance of CT in the preoperative diagnosis of cervical lymph node metastasis in patients with papillary thyroid cancer: a systematic review and meta-analysis[J]. AJNR Am J Neuroradiol, 2017, 38(1): 154-161.   doi: 10.3174/ajnr.A4967
[26] He MZ, Lin CL, Yin L, et al.  Value of dual-energy computed tomography for diagnosing cervical lymph node metastasis in patients with papillary thyroid cancer[J]. J Comput Assist Tomogr, 2019, 43(6): 970-975.   doi: 10.1097/RCT.0000000000000927
[27] Yeh MW, Bauer AJ, Bernet VA, et al.  American Thyroid Association statement on preoperative imaging for thyroid cancer surgery[J]. Thyroid, 2015, 25(1): 3-14.   doi: 10.1089/thy.2014.0096
[28] Hu WJ, Wang H, Wei R, et al.  MRI-based radiomics analysis to predict preoperative lymph node metastasis in papillary thyroid carcinoma[J]. Gland Surg, 2020, 9(5): 1214-1226.   doi: 10.21037/gs-20-479
[29]

Zhang H, Hu SD, Wang X, et al. Using diffusion-weighted MRI to predict central lymph node metastasis in papillary thyroid carcinoma: a feasibility study[J/OL]. Front Endocrinol (Lausanne), 2020, 11: 326[2022-04-24]. https://www.frontiersin.org/articles/10.3389/fendo.2020.00326/full. DOI: 10.3389/fendo.2020.00326.

[30] Xu QF, Liu RC, Wang J, et al.  Role of [99mTc]Tc-Galacto-RGD2 SPECT/CT in identifying metastatic differentiated thyroid carcinoma after thyroidectomy and radioactive iodine therapy[J]. Nucl Med Biol, 2020, 88-89: 34-43.   doi: 10.1016/j.nucmedbio.2020.06.006
[31] Kim DH, Kim SJ.  Diagnostic role of F-18 FDG PET/CT for preoperative lymph node staging in thyroid cancer patients; A systematic review and metaanalysis[J]. Clin Imaging, 2020, 65: 100-107.   doi: 10.1016/j.clinimag.2020.04.030
[32] Zheng K, Liang NX, Zhang JJ, et al.  68Ga-NOTA-PRGD2 PET/CT for integrin imaging in patients with lung cancer[J]. J Nucl Med, 2015, 56(12): 1823-1827.   doi: 10.2967/jnumed.115.160648
[33] 徐震纲, 刘绍严.  分化型甲状腺癌颈侧区淋巴结清扫专家共识(2017版)[J]. 中国实用外科杂志, 2017, 37(9): 985-991.   doi: 10.19538/j.cjps.issn1005-2208.2017.09.13
Xu ZG, Liu SY.  Expert consensus on cervical lymph node dissection for differentiated thyroid carcinoma (2017 edition)[J]. Chin J Pract Surg, 2017, 37(9): 985-991.   doi: 10.19538/j.cjps.issn1005-2208.2017.09.13
[34] Megwalu UC, Orloff LA, Ma YF.  Adjuvant external beam radiotherapy for locally invasive papillary thyroid cancer[J]. Head Neck, 2019, 41(6): 1719-1724.   doi: 10.1002/hed.25639
[35] Roh JL, Kim JM, Park CI.  Central compartment reoperation for recurrent/persistent differentiated thyroid cancer: patterns of recurrence, morbidity, and prediction of postoperative hypocalcemia[J]. Ann Surg Oncol, 2011, 18(5): 1312-1318.   doi: 10.1245/s10434-010-1470-9
[36] Ilhan H, Mustafa M, Bartenstein P, et al.  Rate of elimination of radioiodineavid lymph node metastases of differentiated thyroid carcinoma by postsurgical radioiodine ablation. A bicentric study[J]. Nuklearmedizin, 2016, 55(6): 221-227.   doi: 10.3413/Nukmed-0794-16-01
[37] Wu XY, Gu H, Gao YJ, et al.  Clinical outcomes and prognostic factors of radioiodine ablation therapy for lymph node metastases from papillary thyroid carcinoma[J]. Nucl Med Commun, 2018, 39(1): 22-27.   doi: 10.1097/MNM.0000000000000777
[38] He Y, Pan MZ, Huang JM, et al.  Iodine-131: an effective method for treating lymph node metastases of differentiated thyroid cancer[J]. Med Sci Monit, 2016, 22: 4924-4928.   doi: 10.12659/msm.899028
[39] Lewis BD, Hay ID, Charboneau JW, et al.  Percutaneous ethanol injection for treatment of cervical lymph node metastases in patients with papillary thyroid carcinoma[J]. AJR Am J Roentgenol, 2002, 178(3): 699-704.   doi: 10.2214/ajr.178.3.1780699
[40] Heilo A, Sigstad E, Fagerlid KH, et al.  Efficacy of ultrasound-guided percutaneous ethanol injection treatment in patients with a limited number of metastatic cervical lymph nodes from papillary thyroid carcinoma[J]. J Clin Endocrinol Metab, 2011, 96(9): 2750-2755.   doi: 10.1210/jc.2010-2952
[41] Kim SY, Kim SM, Chang H, et al.  Long-term outcomes of ethanol injection therapy for locally recurrent papillary thyroid cancer[J]. Eur Arch Otorhinolaryngol, 2017, 274(9): 3497-3501.   doi: 10.1007/s00405-017-4660-2
[42] Fontenot TE, Deniwar A, Bhatia P, et al.  Percutaneous ethanol injection vs. reoperation for locally recurrent papillary thyroid cancer: a systematic review and pooled analysis[J]. JAMA Otolaryngol Head Neck Surg, 2015, 141(6): 512-518.   doi: 10.1001/jamaoto.2015.0596
[43] Guang Y, Luo YK, Zhang Y, et al.  Efficacy and safety of percutaneous ultrasound guided radiofrequency ablation for treating cervical metastatic lymph nodes from papillary thyroid carcinoma[J]. J Cancer Res Clin Oncol, 2017, 143(8): 1555-1562.   doi: 10.1007/s00432-017-2386-6
[44] Mauri G, Cova L, Ierace T, et al.  Treatment of metastatic lymph nodes in the neck from papillary thyroid carcinoma with percutaneous laser ablation[J]. Cardiovasc Intervent Radiol, 2016, 39(7): 1023-1030.   doi: 10.1007/s00270-016-1313-6