[1] |
Jagust W.
Imaging the evolution and pathophysiology of Alzheimer disease[J]. Nat Rev NeurosciNat Rev Neurosci, 2018, 19(11): 687-700.
doi: 10.1038/s41583-018-0067-3 |
[2] |
Jagust W.
Time for tau[J]. BrainBrain, 2014, 137(6): 1570-1571.
doi: 10.1093/brain/awu093 |
[3] |
Villemagne VL, Fodero-Tavoletti MT, Masters CL, et al.
Tau imaging: early progress and future directions[J]. Lancet NeurolLancet Neurol, 2015, 14(1): 114-124.
doi: 10.1016/S1474-4422(14)70252-2 |
[4] |
Kolb HC, Andrés JI. Tau positron emission tomography imaging[J/OL]. Cold Spring Harb Perspect Biol, 2017, 9(5): a023721[2019-05-07]. http://cshperspectives.cshlp.org. DOI: 10.1101/cshperspect.a023721. |
[5] |
Xia CF, Arteaga J, Chen G, et al.
[18F]T807, a novel tau positron emission tomography imaging agent for Alzheimer′s disease[J]. Alzheimers DementAlzheimers Dement, 2013, 9(6): 666-676.
doi: 10.1016/j.jalz.2012.11.008 |
[6] |
Chien DT, Bahri S, Szardenings AK, et al.
Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807[J]. J Alzheimers DisJ Alzheimers Dis, 2013, 34(2): 457-468.
doi: 10.3233/JAD-122059 |
[7] |
Thal DR, Vandenberghe R.
Monitoring the progression of Alzheimer's disease with τ-PET[J]. BrainBrain, 2016, 139(5): 1318-1320.
doi: 10.1093/brain/aww057 |
[8] |
Shcherbinin S, Schwarz AJ, Joshi A, et al.
Kinetics of the tau PET tracer 18F-AV-1451 (T807) in subjects with normal cognitive function, mild cognitive impairment, and Alzheimer disease[J]. J Nucl MedJ Nucl Med, 2016, 57(10): 1535-1542.
doi: 10.2967/jnumed.115.170027 |
[9] |
Lowe VJ, Curran G, Fang P, et al. An autoradiographic evaluation of AV-1451 tau PET in dementia[J/OL]. Acta Neuropathol Commun, 2016, 4(1): 58[2019-05-07]. https://actaneurocomms.biomedcentral.com. DOI: 10.1186/s40478-016-0315-6. |
[10] |
Marquié M, Normandin MD, Meltzer AC, et al.
Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies[J]. Ann NeurolAnn Neurol, 2017, 81(1): 117-128.
doi: 10.1002/ana.24844 |
[11] |
Schöll M, Maass A, Mattsson N, et al.
Biomarkers for tau pathology[J]. Mol Cell NeurosciMol Cell Neurosci, 2019, 97: 18-33.
doi: 10.1016/j.mcn.2018.12.001 |
[12] |
Braak H, Braak E.
Neuropathological stageing of Alzheimer-related changes[J]. Acta NeuropatholActa Neuropathol, 1991, 82(4): 239-259.
doi: 10.1007/BF00308809 |
[13] |
Schwarz AJ, Yu P, Miller BB, et al.
Regional profiles of the candidate tau PET ligand 18F-AV-1451 recapitulate key features of Braak histopathological stages[J]. BrainBrain, 2016, 139(5): 1539-1550.
doi: 10.1093/brain/aww023 |
[14] |
Lowe VJ, Wiste HJ, Senjem ML, et al.
Widespread brain tau and its association with ageing, Braak stage and Alzheimer's dementia[J]. BrainBrain, 2018, 141(1): 271-287.
doi: 10.1093/brain/awx320 |
[15] |
Lockhart SN, Schöll M, Baker SL, et al.
Amyloid and tau PET demonstrate region-specific associations in normal older people[J]. NeuroimageNeuroimage, 2017, 150: 191-199.
doi: 10.1016/j.neuroimage.2017.02.051 |
[16] |
Maass, A, Lockhart SN, Harrison TM, et al.
Entorhinal tau pathology, episodic memory decline, and neurodegeneration in aging[J]. J NeurosciJ Neurosci, 2018, 38(3): 530-543.
doi: 10.1523/JNEUROSCI.2028-17.2017 |
[17] |
Buckley RF, Hanseeuw B, Schultz AP, et al.
Region-specific association of subjective cognitive decline with tauopathy independent of global β-amyloid burden[J]. JAMA NeurolJAMA Neurol, 2017, 74(12): 1455-1463.
doi: 10.1001/jamaneurol.2017.2216 |
[18] |
Polanco JC, Li CZ, Bodea LG, et al.
Amyloid-β and tau complexity-towards improved biomarkers and targeted therapies[J]. Nat Rev NeurolNat Rev Neurol, 2018, 14(1): 22-39.
doi: 10.1038/nrneurol.2017.162 |
[19] |
Roberson ED, Scearce-Levie K, Palop JJ, et al.
Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model[J]. ScienceScience, 2007, 316(5825): 750-754.
doi: 10.1126/science.1141736 |
[20] |
Tosun D, Landau S, Aisen PS, et al.
Association between tau deposition and antecedent amyloid-β accumulation rates in normal and early symptomatic individuals[J]. BrainBrain, 2017, 140(5): 1499-1512.
doi: 10.1093/brain/awx046 |
[21] |
Pontecorvo MJ, Devous MD Sr, Navitsky M, et al.
Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition[J]. BrainBrain, 2017, 140(3): 748-763.
doi: 10.1093/brain/aww334 |
[22] |
Koychev I, Gunn RN, Firouzian A, et al.
PET tau and amyloid-β burden in mild Alzheimer's disease: divergent relationship with age, cognition, and cerebrospinal fluid biomarkers[J]. J Alzheimers DisJ Alzheimers Dis, 2017, 60(1): 283-293.
doi: 10.3233/JAD-170129 |
[23] |
Iaccarino L, Tammewar G, Ayakta N, et al. Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's disease[J/OL]. Neuroimage Clin, 2017, 17: 452−464[2019-05-07]. https://www.ncbi.nlm.nih.gov/pmc/journals/2173. DOI: 10.1016/j.nicl.2017.09.016. |
[24] |
Dubois B, Feldman HH, Jacova C, et al.
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria[J]. Lancet NeurolLancet Neurol, 2014, 13(6): 614-629.
doi: 10.1016/S1474-4422(14)70090-0 |
[25] |
Sarazin M, Lagarde J, Bottlaender M.
Distinct tau PET imaging patterns in typical and atypical Alzheimer's disease[J]. BrainBrain, 2016, 139(5): 1321-1324.
doi: 10.1093/brain/aww041 |
[26] |
Ossenkoppele R, Schonhaut DR, Schöll M, et al.
Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease[J]. BrainBrain, 2016, 139(5): 1551-1567.
doi: 10.1093/brain/aww027 |
[27] |
Xia CJ, Makaretz SJ, Caso C, et al.
Association of in vivo [18F]AV-1451 Tau PET imaging results with cortical atrophy and symptoms in typical and atypical Alzheimer disease[J]. JAMA NeurolJAMA Neurol, 2017, 74(4): 427-436.
doi: 10.1001/jamaneurol.2016.5755 |
[28] |
Cho H, Choi JY, Lee HS, et al.
Progressive tau accumulation in Alzheimer's disease: two-year follow-up study[J]. J Nucl MedJ Nucl Med, 2019, 60(11): 1611-1621.
doi: 10.2967/jnumed.118.221697 |
[29] |
Seeley WW, Crawford RK, Zhou J, et al.
Neurodegenerative diseases target large-scale human brain networks[J]. NeuronNeuron, 2009, 62(1): 42-52.
doi: 10.1016/j.neuron.2009.03.024 |
[30] |
Jones DT, Graff-Radford J, Lowe VJ, et al.
Tau, amyloid, and cascading network failure across the Alzheimer's disease spectrum[J]. CortexCortex, 2017, 97: 143-159.
doi: 10.1016/j.cortex.2017.09.018 |
[31] |
Grothe MJ, Teipel SJ.
Spatial patterns of atrophy, hypometabolism, and amyloid deposition in Alzheimer's disease correspond to dissociable functional brain networks[J]. Hum Brain MappHum Brain Mapp, 2016, 37(1): 35-53.
doi: 10.1002/hbm.23018 |
[32] |
Jones DT, Knopman DS, Gunter JL, et al.
Cascading network failure across the Alzheimer's disease spectrum[J]. BrainBrain, 2016, 139(2): 547-562.
doi: 10.1093/brain/awv338 |
[33] |
de Calignon A, Polydoro M, Suárez-Calvet M, et al.
Propagation of tau pathology in a model of early Alzheimer's disease[J]. NeuronNeuron, 2012, 73(4): 685-697.
doi: 10.1016/j.neuron.2011.11.033 |
[34] |
Liu L, Drouet V, Wu JW, et al. Trans-synaptic spread of tau pathology in vivo[J/OL]. PLoS One, 2012, 7(2): e31302[2019-05-07]. http://www.plosone.org. DOI: 10.1371/journal.pone.0031302. |
[35] |
Hoenig MC, Bischof GN, Seemiller J, et al.
Networks of tau distribution in Alzheimer's disease[J]. BrainBrain, 2018, 141(2): 568-581.
doi: 10.1093/brain/awx353 |
[36] |
Hansson O, Grothe MJ, Strandberg TO, et al.
Tau pathology distribution in Alzheimer's disease corresponds differentially to cognition-relevant functional brain networks[J]. Front NeurosciFront Neurosci, 2017, 11: 167-.
doi: 10.3389/fnins.2017.00167 |
[37] |
Wiepert DA, Lowe VJ, Knopman DS, et al. A robust biomarker of large-scale network failure in Alzheimer's disease[J/OL]. Alzheimers Dement(Amst), 2017, 6: 152−161[2019-05-07]. https://alz-journals.onlinelibrary.wiley.com/journal/23528729. DOI: 10.1016/j.dadm.2017.01.004. |
[38] |
Choi JY, Cho H, Ahn SJ, et al.
Off-target 18F-AV-1451 binding in the basal ganglia correlates with age-related iron accumulation[J]. J Nucl MedJ Nucl Med, 2018, 59(1): 117-120.
doi: 10.2967/jnumed.117.195248 |
[39] |
Vermeiren C, Motte P, Viot D, et al.
The tau positron-emission tomography tracer AV-1451 binds with similar affinities to tau fibrils and monoamine oxidases[J]. Mov DisordMov Disord, 2018, 33(2): 273-281.
doi: 10.1002/mds.27271 |
[40] |
Hansen AK, Brooks DJ, Borghammer P, et al.
MAO-B inhibitors do not block in vivo flortaucipir([18F]-AV-1451) binding[J]. Mol Imaging BiolMol Imaging Biol, 2018, 20(3): 356-360.
doi: 10.1007/s11307-017-1143-1 |
[41] |
Marquié M, Verwer EE, Meltzer AC, et al. Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case[J/OL]. Acta Neuropathol Commun, 2017, 5(1): 75[2019-05-07]. https://actaneurocomms.biomedcentral.com. DOI: 10.1186/s40478-017-0482-0. |
[42] |
Wong DF, Comley RA, Kuwabara H, et al.
Characterization of 3 novel tau radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in healthy controls and in Alzheimer subjects[J]. J Nucl MedJ Nucl Med, 2018, 59(12): 1869-1876.
doi: 10.2967/jnumed.118.209916 |
[43] |
Hostetler ED, Walji AM, Zeng ZZ, et al.
Preclinical characterization of 18F-MK-6240, a promising PET tracer for in vivo quantification of human neurofibrillary tangles[J]. J Nucl MedJ Nucl Med, 2016, 57(10): 1599-1606.
doi: 10.2967/jnumed.115.171678 |
[44] |
Kroth H, Oden F, Molette J, et al.
Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies[J]. Eur J Nucl Med Mol ImagingEur J Nucl Med Mol Imaging, 2019, 46(10): 2178-2189.
doi: 10.1007/s00259-019-04397-2 |
[45] |
Jack CR Jr, Bennett DA, Blennow K, et al.
NIA-AA research framework: toward a biological definition of Alzheimer's disease[J]. Alzheimers DementAlzheimers Dement, 2018, 14(4): 535-562.
doi: 10.1016/j.jalz.2018.02.018 |